Inhibition of multidrug resistance proteins by MK571 restored the erectile function in obese mice through cGMP accumulation.

de Oliveira, Mariana Gonçalves; Passos, Gabriela Reolon; de Gomes, Erick de Toledo; Leonardi, Guilherme Ruiz; Zapparoli, Adriana; Antunes, Edson; Mónica, Fabiola Zakia

de Oliveira, Mariana Gonçalves; Passos, Gabriela Reolon; de Gomes, Erick de Toledo; Leonardi, Guilherme Ruiz; Zapparoli, Adriana; Antunes, Edson; Mónica, Fabiola Zakia.

Afiliação

de Oliveira MG; Department of Translation Medicine (Pharmacology area), Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Passos GR; Department of Translation Medicine (Pharmacology area), Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
de Gomes ET; Department of Translation Medicine (Pharmacology area), Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Leonardi GR; Department of Translation Medicine (Pharmacology area), Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Zapparoli A; Department of Translation Medicine (Pharmacology area), Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Antunes E; Department of Translation Medicine (Pharmacology area), Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Mónica FZ; Department of Translation Medicine (Pharmacology area), Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.

Andrology ; 11(3): 611-620, 2023 03.

Article em En | MEDLINE | ID: mdl-36375168

Assuntos

Disfunção Erétil; Masculino; Humanos; Camundongos; Animais; Disfunção Erétil/tratamento farmacológico; Subfamília B de Transportador de Cassetes de Ligação de ATP/uso terapêutico; Tadalafila/farmacologia; Tadalafila/uso terapêutico; Camundongos Obesos; Nitroprussiato/farmacologia; Nitroprussiato/metabolismo; Nitroprussiato/uso terapêutico; GMP Cíclico/metabolismo; Acetilcolina/farmacologia; Acetilcolina/uso terapêutico; Obesidade

Palavras-chave

ATP-binding cassette transporter; MK571; MRP4; MRP5; cGMP; corpus cavernosum; erectile dysfunction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Disfunção Erétil Limite: Animals / Humans / Male Idioma: En Revista: Andrology Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

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