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Nutritional Characterization, Antioxidant, and Lipid-Lowering Effects of Yellow Mombin (Spondias mombin) Supplemented to Rats Fed a High-Fat Diet.
Lucena, Tatiana Luiza Costa; Batista, Kamila Sabino; Pinheiro, Rafael Oliveira; Cavalcante, Hassler Clementino; Gomes, Jéssyca Alencar de Sousa; Silva, Laiane Alves da; Lins, Priscilla Paulo; Ferreira, Fabrícia Souza; Lima, Rafael Ferreira; Lima, Marcos Dos Santos; Aquino, Jailane de Souza.
Afiliação
  • Lucena TLC; Experimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
  • Batista KS; Experimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
  • Pinheiro RO; Post Graduate Program in Nutrition Sciences, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
  • Cavalcante HC; Experimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
  • Gomes JAS; Post Graduate Program in Nutrition Sciences, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
  • Silva LAD; Experimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
  • Lins PP; Post Graduate Program in Nutrition Sciences, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
  • Ferreira FS; Experimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
  • Lima RF; Experimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
  • Lima MDS; Experimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
  • Aquino JS; Experimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, Brazil.
Foods ; 11(19)2022 Oct 02.
Article em En | MEDLINE | ID: mdl-36230142
The aim of this study was to evaluate the effects of supplementing yellow mombin (YM) on the oxidative, somatic, and lipid parameters in rats fed a high-fat diet. A total of 24 adult Wistar rats were randomized into three groups: normal-fat diet (NF), high-fat diet (HF), and high-fat diet with YM supplementation (HFYM). Diets were administered for four weeks, and YM (400 mg/kg) was supplemented via gavage in the last two weeks of the experiment. After the four-week period, the somatic, serum biochemical, and liver oxidative parameters were evaluated. YM has a high antioxidant activity and significant amounts of phenolic compounds, carotenoids, vitamin C, dietary fibre, and minerals. The HFYM group had the lowest body weight (18.75%), body mass index (17.74%), and adiposity (31.63%) compared with the HF group. YM supplementation reduced low-density lipoprotein by 43.05% and increased high-density lipoprotein by 25.73%, but did not improve the triglyceride levels in the serum. YM treatment improved glucose tolerance and lipid peroxidation, and also enhanced the antioxidant capacity, superoxide dismutase, and glutathione peroxidase activities in the liver. These results indicate the lipid-lowering property and potential antioxidant activity of YM against liver oxidative damage caused by a high-fat diet intake, which may be associated with the bioactive compounds present in this fruit.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Idioma: En Revista: Foods Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Idioma: En Revista: Foods Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça