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Implantation of heat treatment Ti6al4v alloys in femoral bone of Wistar rats.
Chávez Díaz, Mercedes Paulina; Henche, Soledad Aguado; Yanchuck, Mónica Rubio; de Arriba, Celia Clemente; Sierra, Román Cabrera; Rincón, María Lorenza Escudero; Hallen, José M.
Afiliação
  • Chávez Díaz MP; Centro de Estudios Científicos y Tecnológicos Número 7 Cuauhtémoc (CECyT 7), Ermita Iztapalapa 3241, Sta. María Aztahuacan, Iztapalapa, Ciudad de México, 09570, Mexico. mpchavez@ipn.mx.
  • Henche SA; Centro Nacional de Investigaciones Metalúrgicas (CENIM-CSIC). Departamento de Ingeniería de Superficies, Corrosión y Durabilidad, 28040, Madrid, Spain. mpchavez@ipn.mx.
  • Yanchuck MR; Departamento de Cirugía, Ciencias Médicas y Sociales. Área Anatomía y Embriología Humana de la Facultad de Medicina, Universidad de Alcalá (UAH), Ctra. Mad-Barc Km 33,600. Campus Universitario, Alcalá de Henares, 28805, Madrid, Spain.
  • de Arriba CC; Hospital Universitario La Paz. Servicio de Cirugía Plástica, Reparadora y Quemados, Paseo de la Castellana 261, 28046, Madrid, Spain.
  • Sierra RC; Departamento de Cirugía, Ciencias Médicas y Sociales. Área Anatomía y Embriología Humana de la Facultad de Medicina, Universidad de Alcalá (UAH), Ctra. Mad-Barc Km 33,600. Campus Universitario, Alcalá de Henares, 28805, Madrid, Spain.
  • Rincón MLE; Departamento de Ingeniería Química Industrial y Metalurgia y Materiales, UPALM Edificio 7, Instituto Politécnico Nacional, Ciudad de México, 07738, Mexico.
  • Hallen JM; Centro Nacional de Investigaciones Metalúrgicas (CENIM-CSIC). Departamento de Ingeniería de Superficies, Corrosión y Durabilidad, 28040, Madrid, Spain.
J Mater Sci Mater Med ; 33(10): 70, 2022 Oct 03.
Article em En | MEDLINE | ID: mdl-36190567
Two heat treatments were carried out at below (Ti6Al4V800) and above (Ti6Al4V1050) the beta-phase transformation temperature (TTRANSUS = 980 °C), to study the effect of microstructural changes on osseointegration. The alloys were implanted in the femurs of hind legs of Wistar rats for 15, 30, and 60 days. Histology of the femur sections obtained for the first 15 days showed inflammatory tissue surrounding the implants and tissue contraction, which prevented osseointegration in early stages. After 30 days, trabecular bone, reduction of inflammatory tissue around the implants, and osseointegration were observed in Ti6Al4V as received and Ti6Al4V1050 alloys, while osseointegration was detected for the three alloys after 60 days. These results were supported through morphometric studies based on the analysis of Bone Implant Contact (BIC), where there was a larger bone contact after 60 days for the Ti6Al4V1050 alloy; indicating that microstructural features of the Ti6Al4V alloys influence their osseointegration, with the lamellar microstructure (Ti6Al4V1050), being the most responsive. Graphical abstract.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ligas / Temperatura Alta Limite: Animals Idioma: En Revista: J Mater Sci Mater Med Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ligas / Temperatura Alta Limite: Animals Idioma: En Revista: J Mater Sci Mater Med Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos