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Uveitis and nail psoriasis in a patient without articular involvement: a case report.
Pineda-Sierra, Juan Sebastián; Peña-Pulgar, Luisa Fernanda; Cifuentes-González, Carlos; Rojas-Carabali, William; de-la-Torre, Alejandra.
Afiliação
  • Pineda-Sierra JS; Neuroscience Research Group (NEUROS), Neurovitae Research Center, Escuela de Medicina Y Ciencias de La Salud, Universidad del Rosario, Carrera 24 # 63C-69, Bogotá, Colombia.
  • Peña-Pulgar LF; Ophthalmology Interest Group, Neuroscience Research Group (NEUROS), Neurovitae Research Center, Escuela de Medicina Y Ciencias de La Salud, Universidad del Rosario, Bogotá, Colombia.
  • Cifuentes-González C; Neuroscience Research Group (NEUROS), Neurovitae Research Center, Escuela de Medicina Y Ciencias de La Salud, Universidad del Rosario, Carrera 24 # 63C-69, Bogotá, Colombia.
  • Rojas-Carabali W; Ophthalmology Interest Group, Neuroscience Research Group (NEUROS), Neurovitae Research Center, Escuela de Medicina Y Ciencias de La Salud, Universidad del Rosario, Bogotá, Colombia.
  • de-la-Torre A; Neuroscience Research Group (NEUROS), Neurovitae Research Center, Escuela de Medicina Y Ciencias de La Salud, Universidad del Rosario, Carrera 24 # 63C-69, Bogotá, Colombia.
BMC Ophthalmol ; 22(1): 384, 2022 Sep 24.
Article em En | MEDLINE | ID: mdl-36153505
BACKGROUND: This study aimed to report a case of bilateral anterior non-granulomatous chronic non-infectious uveitis associated with isolated nail psoriasis without articular involvement. CASE PRESENTATION: A 55-year-old man with a history of open-angle glaucoma was referred to our uveitis and ocular immunology center with intraocular inflammation concordant with chronic non-infectious bilateral anterior non-granulomatous uveitis. At presentation, he had moderate inflammation in the anterior chamber bilaterally and lesions characteristic of nail psoriasis. Nail psoriasis was later confirmed by nail ultrasonography performed by a radiologist who specialized in psoriasis. Appropriate clinical and paraclinical assessments were conducted, ruling out all other possible causes of uveitis. The patient required dual systemic immunomodulatory therapy with methotrexate and adalimumab, topical anti-inflammatory drugs (steroidal and non-steroidal), and anti-glaucoma therapy to achieve satisfactory inflammatory and ocular pressure control. DISCUSSION AND CONCLUSIONS: This is the first report of non-infectious uveitis associated with nail compromise in a patient without other manifestations of psoriasis. Despite reports on the relationship between psoriatic disease and uveitis, there is insufficient information on clinical phenotypes associated with uveitis that could lead to later diagnosis and treatment of associated intraocular inflammation. Clinicians should be aware of all subtypes of psoriasis that increases a risk of developing uveitis in these patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Uveíte / Uveíte Anterior / Glaucoma de Ângulo Aberto Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Humans / Male Idioma: En Revista: BMC Ophthalmol Assunto da revista: OFTALMOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Uveíte / Uveíte Anterior / Glaucoma de Ângulo Aberto Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Humans / Male Idioma: En Revista: BMC Ophthalmol Assunto da revista: OFTALMOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Reino Unido