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Spin and reporting in systematic reviews with meta-analysis of randomized clinical trials in restorative dentistry.
Sensever, Felipe de Araújo; de Lucena Alves, Charles Phillipe; Lima, Giana da S; Loomans, Bas; Opdam, Niek; Pereira-Cenci, Tatiana.
Afiliação
  • Sensever FA; Graduate Program in Dentistry, Federal University of Pelotas, R. Gonçalves Chaves 457, Pelotas 96015-560, Brazil.
  • de Lucena Alves CP; Postgraduate Program in Epidemiology, Federal University of Pelotas, R. Mal Deodoro, 1160, Pelotas, RS 96020-220, Brazil.
  • Lima GDS; Graduate Program in Dentistry, Federal University of Pelotas, R. Gonçalves Chaves 457, Pelotas 96015-560, Brazil.
  • Loomans B; Department of Dentistry, Radboud Institute for Health Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, Nijmegen 6525 EX, the Netherlands.
  • Opdam N; Department of Dentistry, Radboud Institute for Health Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, Nijmegen 6525 EX, the Netherlands.
  • Pereira-Cenci T; Graduate Program in Dentistry, Federal University of Pelotas, R. Gonçalves Chaves 457, Pelotas 96015-560, Brazil; Department of Dentistry, Radboud Institute for Health Sciences, Radboud University Medical Center, Philips van Leydenlaan 25, Nijmegen 6525 EX, the Netherlands. Electronic address: Tatia
J Dent ; 125: 104282, 2022 10.
Article em En | MEDLINE | ID: mdl-36084762
OBJECTIVE: To estimate the prevalence of spin and completeness of reporting of systematic reviews with metanalysis (SRMAs) in restorative dentistry. METHODS: Inclusion criteria were SRMAs of randomized clinical trials of restorative dentistry on survival, success, or failure rates of treatment in humans, with no language or year restriction. SRMAs performed with non-RCTs were excluded. PubMed/MEDLINE, Web of Science, Scopus, Embase, and Cochrane Collaboration Library were searched from inception to April 2022. Outcomes were the prevalence of spin (primary outcome) and completeness of reporting (secondary outcome) in the abstract and full text. Data were reported through means and standard deviations or absolute and relative frequencies. Spin in each item was considered low when occurring in less than 25% of the papers, moderate (25 to 75%), or high (more than 75%). RESULTS: We identified 7029 studies and 49 unique manuscripts were included. There was a moderate presence of spin in the abstracts and low in full texts. In the abstracts, 65.9% did not report adverse events; while in the abstract and full text, more than 16% reported a conclusion containing recommendations for clinical practice not supported by the findings. Regarding completeness of reporting, there was poor reporting for most items in the abstract while there was an adequate report in full texts, except for register name and registration number (not reported in 32.7%). CONCLUSIONS: Abstract of SRMAs in restorative dentistry should be better reported. Spin and poor reporting were more frequent in the abstracts, which misleads readers and could lead to inadequate clinical recommendations. CLINICAL SIGNIFICANCE: Spin and incomplete reporting are a threat to evidence-based practice, especially in systematic reviews. Therefore, care providers, researchers, and other stakeholders should be aware of the possibility of spin in systematic reviews and other sources to prevent misinterpretation, which could lead to inadequate decisions and treatments.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Odontologia / Relatório de Pesquisa Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Revista: J Dent Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Odontologia / Relatório de Pesquisa Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Revista: J Dent Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido