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Virtual Memory CD8+ T Cells: Origin and Beyond.
Viano, Maria Estefania; Baez, Natalia Soledad; Savid-Frontera, Constanza; Lidon, Nicolás Leonel; Hodge, Deborah L; Herbelin, André; Gombert, Jean-Marc; Barbarin, Alice; Rodriguez-Galan, Maria Cecilia.
Afiliação
  • Viano ME; Inmunología, CIBICI-CONICET, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
  • Baez NS; Inmunología, CIBICI-CONICET, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
  • Savid-Frontera C; Inmunología, CIBICI-CONICET, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
  • Lidon NL; Inmunología, CIBICI-CONICET, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
  • Hodge DL; National Institutes of Health, Bethesda, Maryland, USA.
  • Herbelin A; Inserm U1313, Poitiers, France.
  • Gombert JM; Université de Poitiers, Poitiers, France.
  • Barbarin A; Inserm U1313, Poitiers, France.
  • Rodriguez-Galan MC; Université de Poitiers, Poitiers, France.
J Interferon Cytokine Res ; 42(12): 624-642, 2022 12.
Article em En | MEDLINE | ID: mdl-36083273
The presence of CD8+ T cells with a memory phenotype in nonimmunized mice has been noted for decades, but it was not until about 2 decades ago that they began to be studied in greater depth. Currently called virtual memory CD8+ T cells, they consist of a heterogeneous group of cells with memory characteristics, without any previous contact with their specific antigens. These cells were identified in mice, but a few years ago, a cell type with characteristics equivalent to the murine ones was described in healthy humans. In this review, we address the different aspects of its biology mainly developed in murine models and what is currently known about its cellular equivalent in humans.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD8-Positivos / Memória Imunológica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Interferon Cytokine Res Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Argentina País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD8-Positivos / Memória Imunológica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Interferon Cytokine Res Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Argentina País de publicação: Estados Unidos