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Comparison of two oxygen saturation targets to decide on hospital discharge of infants with viral bronchiolitis living at high altitudes: a cost-effectiveness analysis.
Rodriguez-Martinez, Carlos E; Sossa-Briceño, Monica P; Antonio Buendia, Jefferson.
Afiliação
  • Rodriguez-Martinez CE; Department of Pediatrics, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia.
  • Sossa-Briceño MP; Department of Pediatric Pulmonology, School of Medicine, Universidad El Bosque, Bogota, Colombia.
  • Antonio Buendia J; Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia.
Curr Med Res Opin ; 38(12): 2047-2053, 2022 12.
Article em En | MEDLINE | ID: mdl-35993483
OBJECTIVES: The objective of the current study was to evaluate the cost-effectiveness of two pulse oximetry (SpO2) thresholds to decide on hospital discharge when all other discharge criteria are met, in infants with viral bronchiolitis living at high altitudes. METHODS: A decision analysis model was developed to estimate the cost-effectiveness of the use of an SpO2 threshold of 90% versus one of 85% for deciding whether infants hospitalized for viral bronchiolitis can be safely discharged to home, from a third-party payer's perspective. The main outcome was discharge to home at day 4 of the initial hospitalization. The time horizon was 28 days after discharge from hospital. We performed deterministic sensitivity analyses and probabilistic sensitivity analyses. RESULTS: Compared to the use of an SpO2 threshold of 90%, treating infants with viral bronchiolitis with the use of an SpO2 threshold of 85% resulted in lower total costs (US$119.39 vs. US$188.357 mean cost per patient) and a greater probability of discharge to home at day 4 of the initial hospitalization (0.8400 vs. 0.7600), therefore being a dominant strategy. Sensitivity analyses were in line with base case results. CONCLUSIONS: In Bogota, a high-altitude city, in infants admitted for viral bronchiolitis, the use of an SpO2 threshold of 85% to decide on hospital discharge when all other discharge criteria are met is dominant because it entails a greater probability of discharge to home at day 4 of the initial hospitalization and generates fewer costs than the use of an SpO2 threshold of 90%.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bronquiolite / Bronquiolite Viral Tipo de estudo: Health_economic_evaluation / Prognostic_studies Limite: Humans / Infant Idioma: En Revista: Curr Med Res Opin Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bronquiolite / Bronquiolite Viral Tipo de estudo: Health_economic_evaluation / Prognostic_studies Limite: Humans / Infant Idioma: En Revista: Curr Med Res Opin Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Reino Unido