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Neuropathic Pain Relief after Surgical Neurolysis in Patients with Traumatic Brachial Plexus Injuries: A Preliminary Report.
Armas-Salazar, Armando; Téllez-León, Noe; García-Jerónimo, Ana Isabel; Villegas-López, Francisco Alberto; Navarro-Olvera, José Luis; Carrillo-Ruiz, José Damián.
Afiliação
  • Armas-Salazar A; Mexican Faculty of Medicine of La Salle University, Mexico City, Mexico.
  • Téllez-León N; Postgraduate Department, School of Higher Education in Medicine, National Polytechnic Institute, Mexico City, Mexico.
  • García-Jerónimo AI; Functional & Stereotactic Neurosurgery & Radiosurgery Service, General Hospital of México, Mexico City, Mexico.
  • Villegas-López FA; Physical Medicine & Rehabilitation Service, General Hospital of México, Mexico City, Mexico.
  • Navarro-Olvera JL; Functional & Stereotactic Neurosurgery & Radiosurgery Service, General Hospital of México, Mexico City, Mexico.
  • Carrillo-Ruiz JD; Functional & Stereotactic Neurosurgery & Radiosurgery Service, General Hospital of México, Mexico City, Mexico.
Pain Res Manag ; 2022: 5660462, 2022.
Article em En | MEDLINE | ID: mdl-35958676
Objective: To evaluate the usefulness of surgical neurolysis for neuropathic pain relief in patients with posttraumatic brachial plexus injury (BPI). Methods: A prospective, longitudinal, nonrandomized, self-controlled before and after study was performed to evaluate the pain changes according to their intensity using the Visual Analogue Scale (VAS), and the sensory recovery after surgery using the British Medical Research Council (BMRC) scale for sensory recovery. To establish significant changes, a paired T-test was performed, and in order to determine the magnitude of these changes, an effect size was measured. α = 0.05. Results: Ten patients were included with an average follow-up of 61.9 ± 53.62 months. The main mechanism of injury was vehicular trauma (70%). A significant decrease in pain after the surgical intervention was observed resulting from an average preoperative state according to VAS of 8.4 ± 1.58, to a postoperative state of 3.4 ± 3.27 (59.52%, p = 0.005, Δ = 1.572), added to a mean sensory improvement (25%) from 2.8 ± 1.62 to 3.5 ± 0.97 after surgery according to BMRC, without statistically significant changes (p=0.062), showing a moderate effect size (Δ = 0.413). Almost all patients showed improvement in the continuous and paroxysmal pattern of pain. No postoperative complications were observed. Discussion. These results suggest that in cases of BPI that originates from a compressive syndrome secondary to the posttraumatic fibrosis that surrounds the nerve structures causing strangulation and inducing hypernociception, the use of surgical neurolysis is an appropriate alternative for patients with medically refractory neuropathic pain.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plexo Braquial / Neuralgia Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies Limite: Humans Idioma: En Revista: Pain Res Manag Assunto da revista: NEUROLOGIA / PSICOFISIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plexo Braquial / Neuralgia Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies Limite: Humans Idioma: En Revista: Pain Res Manag Assunto da revista: NEUROLOGIA / PSICOFISIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos