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Resistance to obesity prevents obesity development without increasing spontaneous physical activity and not directly related to greater metabolic and oxidative capacity.
Pimentel Cordeiro, Jóctan; da Silva, Daniel Sesana; Torezani-Sales, Suellem; Madureira, Amanda Rangel; Claudio, Erick Roberto Gonçalves; Bocalini, Danilo Sales; Lima-Leopoldo, Ana Paula; Leopoldo, André Soares.
Afiliação
  • Pimentel Cordeiro J; Center for Physical Education and Sports, Experimental Physiology and Biochemistry Laboratory, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
  • da Silva DS; Center for Physical Education and Sports, Experimental Physiology and Biochemistry Laboratory, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
  • Torezani-Sales S; Postgraduate Program in Nutrition and Health, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
  • Madureira AR; Postgraduate Program in Nutrition and Health, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
  • Claudio ERG; Postgraduate Program in Physiological Science, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
  • Bocalini DS; Center for Physical Education and Sports, Experimental Physiology and Biochemistry Laboratory, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
  • Lima-Leopoldo AP; Center for Physical Education and Sports, Experimental Physiology and Biochemistry Laboratory, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
  • Leopoldo AS; Postgraduate Program in Nutrition and Health, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
PLoS One ; 17(8): e0271592, 2022.
Article em En | MEDLINE | ID: mdl-35951512
There are evidence that obese-resistant animals are more physically active, due to a higher rate of lipid oxidation. Efficiency in such pathways can favor greater spontaneous physical activity and, consequently, less body fat deposition. The aim of study was characterizing the nutritional profile and spontaneous physical activity in the condition of Resistance to Obesity (OR). Wistar rats were randomized into standard diet (SD; n = 50) and high-fat diet (HFD; n = 50) groups, after obesity induction, were redistributed into Control (C), False-control (FC), Propensity to obesity (OP) and OR, and then spontaneous physical activity was evaluated. Analyzed parameters: body mass (BM), epididymal (EF), retroperitoneal (RF), visceral (VF) and respective summations (∑), adiposity index (AI), nutritional, morphological, biochemical and metabolic parameters and protein quantification. The comparison of the groups was performed by ANOVA one or two factors, with 5% significance adopted. OP and FC presented high final MC values compared to C and OR. OR had lower EF, RF, VF, ∑ and IA compared to OP. OR had similar values to C and higher HDL than FC and OP. In GTT, OR and C presented similar values and both were lower than OP in the 30 minutes. OP promoted higher values than C for glycemic AUC. OR had higher PPARγ content than C and OP, as well as levels similar to C for leptin and insulin. Spontaneous physical activity did not differ between groups. The results were not enough to show that OR animals have greater lipid oxidative capacity, as well as greater spontaneous physical activity.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dieta Hiperlipídica / Obesidade Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dieta Hiperlipídica / Obesidade Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos