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Critical CHD screening programme: a 3-year multicentre experience in Mexico.
Gómez-Gutiérrez, René; Galindo-Hayashi, José M; Cantú-Reyna, Consuelo; Vazquez-Cantu, Diana L; Britton-Robles, Cecilia; Cruz-Camino, Héctor.
Afiliação
  • Gómez-Gutiérrez R; Genomi-k, Monterrey, Nuevo León, 64060, Mexico.
  • Galindo-Hayashi JM; CHRISTUS Muguerza, Hospital Alta Especialidad, Monterrey, Nuevo León, 64060, Mexico.
  • Cantú-Reyna C; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León, 64710, Mexico.
  • Vazquez-Cantu DL; Genomi-k, Monterrey, Nuevo León, 64060, Mexico.
  • Britton-Robles C; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León, 64710, Mexico.
  • Cruz-Camino H; Genomi-k, Monterrey, Nuevo León, 64060, Mexico.
Cardiol Young ; : 1-7, 2022 Jul 08.
Article em En | MEDLINE | ID: mdl-35801272
INTRODUCTION: CHDs are the most common type of birth defect. One in four newborns with a heart defect has a critical CHD. In Mexico, there is a lack of data available to determine its prevalence. Pulse oximetry screening programmes have been implemented worldwide, reporting opportunity areas in algorithm interpretation and data management. Our study aims to share preliminary results of a 3-year experience of a multicentre pulse oximetry screening programme that addresses critical challenges. MATERIALS AND METHODS: This retrospective study examined the reports of newborns screened from February 2016 to July 2019 from five hospitals. Two algorithms -the New Jersey and the American Academy of Pediatrics- were implemented over consecutive periods. The algorithms' impact was assessed through the calculation of the false-positive rate in an eligible population. RESULTS: A total of 8960 newborns were eligible for the study; from it, 32.27% were screened under the New Jersey and 67.72% under the American Academy of Pediatrics algorithm - false-positive rate: 1% (CI 95: ± 0.36%) and 0.71% (CI 95: ± 0.21%), respectively. Seventy-nine newborns were referred, six were diagnosed with critical CHD, and six with CHD. The critical CHD estimated prevalence was 6.69:10,000 newborns (CI 95: ± 5.36). Our results showed that the algorithm was not related to the observable false-positive rate reduction. DISCUSSION: Other factors may play a role in decreasing the false-positive rate. Our experience implementing this programme was that a systematic screening process led to more confident results, newborn's report interpretation, and follow-up.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies / Screening_studies País/Região como assunto: Mexico Idioma: En Revista: Cardiol Young Assunto da revista: ANGIOLOGIA / CARDIOLOGIA / PEDIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies / Screening_studies País/Região como assunto: Mexico Idioma: En Revista: Cardiol Young Assunto da revista: ANGIOLOGIA / CARDIOLOGIA / PEDIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido