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Brachytherapy for Central Serous Chorioretinopathy.
Arora, Supriya; Stea, Baldassarre D; Hamilton, Russell J; Chhablani, Jay.
Afiliação
  • Arora S; Bahamas Vision Center and Princess Margaret Hospital, Nassau, NP, Bahamas.
  • Stea BD; Department of Radiation Oncology, University of Arizona, Tucson, AZ, 85719, USA.
  • Hamilton RJ; Department of Radiation Oncology, University of Arizona, Tucson, AZ, 85719, USA.
  • Chhablani J; UPMC Eye Center, University of Pittsburgh, Pittsburgh, USA. jay.chhablani@gmail.com.
Ophthalmol Ther ; 11(5): 1611-1616, 2022 Oct.
Article em En | MEDLINE | ID: mdl-35793036
Brachytherapy is widely used for the treatment of choroidal melanoma and has recently been explored for the treatment of wet age-related macular degeneration. We propose the use of low dose radiation via episcleral brachytherapy in refractory cases of central serous chorioretinopathy (CSCR). The pathogenesis of CSCR involves dilatation and hyperpermeability of large choroidal vessels. Low dose radiation can induce intimal proliferation in large choroidal vessels and decrease their hyperpermeability. Concerns about the use of brachytherapy in CSCR include damage to the choriocapillaris or the retinal vessels. This can be addressed with the use of a specialized device through which a very precise and appropriate dose can be delivered. The dose of the radiation delivered decreases exponentially at a depth of approximately 0.5-1.5 mm from the devise-sclera interface. Considering an increased choroidal thickness in cases of CSCR, delivery of a safe dose can be assured.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Ophthalmol Ther Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Bahamas País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Ophthalmol Ther Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Bahamas País de publicação: Reino Unido