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Evaluation of Different Polymerisation Methods of Ocular Prosthesis Acrylic Resins on Subcutaneous Tissue Inflammatory Response in Rats.
da Silva, Emily V F; Goiato, Marcelo C; Bitencourt, Sandro B; Brito, Victor G B; Takamyia, Aline S; Penitente, Paulo A; de Oliveira, Sandra H P; Dos Santos, Daniela M.
Afiliação
  • da Silva EVF; Department of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.
  • Goiato MC; Department of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.
  • Bitencourt SB; Department of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.
  • Brito VGB; Department of Basic Sciences, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.
  • Takamyia AS; Department of Surgery and Integrated Clinic, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.
  • Penitente PA; Department of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.
  • de Oliveira SHP; Department of Basic Sciences, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.
  • Dos Santos DM; Department of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.
Sultan Qaboos Univ Med J ; 22(2): 233-240, 2022 May.
Article em En | MEDLINE | ID: mdl-35673290
Objectives: This study aimed to evaluate the influence of different polymerisation methods of acrylic resin for ocular prostheses on the subcutaneous tissue inflammatory response of rats. Methods: The study was conducted at the Basic Sciences Department, Araçatuba Dental School, São Paulo State University (UNESP), Brazil, from 2016 to 2018. The samples were prepared by water bath (WB), microwave energy (MW) or autopolymerisation (AP) (n = 20 samples per group). The inflammatory response (cell count and immunohistochemical analysis of interleukin [IL]-1ß, IL-6, tumour necrosis factor [TNF]-α, IL-17 and macrophage inflammatory protein-3α) was analysed by the implantation of a sample from each group in the subcutaneous tissue of 20 Wistar rats and evaluated after seven, 15, 30 and 60 days. The quantitative and qualitative data were analysed using analysis of variance and Tukey tests (P <0.05) and visual comparison, respectively. Results: There was a moderate inflammatory infiltrate for the MW and AP groups and a light infiltrate for the WB group after seven days. The inflammatory infiltrate and the immunolabeling of tested targets decreased gradually during the 60-day period. The AP group had the highest immunolabeling of TNF-α (seven days), IL-1ß and IL-17 (at 15 and 30 days) and IL-6 (at 30 and 60 days). The WB and MW groups showed greater immunolabeling at 15 and 30 days, while the MW group also had high results at 60 days. Conclusion: Polymerisation by microwave energy and by chemical activation resulted in a higher inflammatory response.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resinas Acrílicas / Olho Artificial Tipo de estudo: Qualitative_research Limite: Animals / Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Sultan Qaboos Univ Med J Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Omã
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resinas Acrílicas / Olho Artificial Tipo de estudo: Qualitative_research Limite: Animals / Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Sultan Qaboos Univ Med J Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Omã