ATG5, autophagy-related 5; Acetyl-H3, acetyl-histone 3; Atherosclerosis; Autophagy; BET, bromodomain and extra-terminal; BRD4; BRD4, bromodomain protein 4; CQ, chloroquine; CVDs, cardiovascular diseases; ChIP, chromatin immunoprecipitation; Cur, curcumin; Curcumin; Dil-ox-LDL, 1,1'-dioctadecyl-3,3,3',3'-tetramethy-lindocarbocyanine perchlorate labeled oxidized low-density lipoprotein; FCs, foam cells; HFD, high-fat diet; IL-1ß, interleukin 1ß; Inflammation; LIR, LC3-interacting region; MCP-1, monocyte chemotactic protein 1; Macrophage; NAC, N-acetyl-l-cysteine; ORO, Oil red O; P300; ROS, reactive oxygen species; Re-ChIP, re-chromatin immunoprecipitation; SE, super-enhancer; TFEB; TFEB, transcription factor EB; TNF-α, tumor necrosis factor α; mTORC1, mammalian target of rapamycin complex 1; ox-LDL, oxidized low-density lipoprotein; qRT-PCR, quantitative real-time polymerase chain reaction; siRNAs, small interference RNAs