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Biological Effects of Animal Venoms on the Human Immune System.
Avalo, Zharick; Barrera, María Claudia; Agudelo-Delgado, Manuela; Tobón, Gabriel J; Cañas, Carlos A.
Afiliação
  • Avalo Z; Escuela de Bacteriología, Facultad de Salud, Universidad del Valle, Cali 76001, Colombia.
  • Barrera MC; Department de Microbiología, Universidad del Valle, Cali 76001, Colombia.
  • Agudelo-Delgado M; Escuela de Bacteriología, Facultad de Salud, Universidad del Valle, Cali 76001, Colombia.
  • Tobón GJ; Department of Medical Microbiology, Southern Illinois University School of Medicine, Springfield, IL 62901, USA.
  • Cañas CA; Unidad de Reumatología, Fundación Valle del Lili, Cali 760032, Colombia.
Toxins (Basel) ; 14(5)2022 05 16.
Article em En | MEDLINE | ID: mdl-35622591
Venoms are products of specialized glands and serve many living organisms to immobilize and kill prey, start digestive processes and act as a defense mechanism. Venoms affect different cells, cellular structures and tissues, such as skin, nervous, hematological, digestive, excretory and immune systems, as well as the heart, among other structures. Components of both the innate and adaptive immune systems can be stimulated or suppressed. Studying the effects on the cells and molecules produced by the immune system has been useful in many biomedical fields. The effects of venoms can be the basis for research and development of therapeutic protocols useful in the modulation of the immunological system, including different autoimmune diseases. This review focuses on the understanding of biological effects of diverse venom on the human immune system and how some of their components can be useful for the study and development of immunomodulatory drugs.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Líquidos Corporais Tipo de estudo: Guideline Limite: Animals / Humans Idioma: En Revista: Toxins (Basel) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Líquidos Corporais Tipo de estudo: Guideline Limite: Animals / Humans Idioma: En Revista: Toxins (Basel) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Suíça