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Evaluation of pulse wave velocity and central systolic blood pressure in children and adolescents with chronic kidney disease.
Brecheret, Ana Paula; Abreu, Ana Lucia Cardoso Santos; Lopes, Renata; Fonseca, Francisco Antônio Helfenstein; Solé, Dirceu; Andrade, Maria Cristina de.
Afiliação
  • Brecheret AP; Universidade Federal de São Paulo, São Paulo, SP, Brazil.
  • Abreu ALCS; Universidade Federal de São Paulo, São Paulo, SP, Brazil.
  • Lopes R; Universidade Federal de São Paulo, São Paulo, SP, Brazil.
  • Fonseca FAH; Universidade Federal de São Paulo, São Paulo, SP, Brazil.
  • Solé D; Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
  • Andrade MC; Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Einstein (Sao Paulo) ; 20: eAO6758, 2022.
Article em En | MEDLINE | ID: mdl-35544895
OBJECTIVE: Investigate pulse wave velocity and central systolic blood pressure among pediatric population with chronic kidney disease. METHODS: In this cross-sectional study, 57 patients (61.4% male) aged 6.2 to 17.5 years old, 44 with nondialysis chronic kidney disease and 13 on chronic dialysis, were included in the analysis. The pulse wave velocity and the central systolic blood pressure were measured with an oscillometric device with an inbuilt ARC SolverⓇ algorithm and were compared with previously established percentiles. RESULTS: The prevalence of elevated pulse wave velocity was 21.1% (95%Cl: 11.4-33.9) and elevated central systolic blood pressure was 28.1% (95%CI: 17.0-41.5). According to the generalized linear model, there was a higher risk of elevated pulse wave velocity in patients undergoing chronic dialysis treatment than nondialysis chronic kidney disease patients (adjPR=4.24, 95%CI: 1.97-9.13, p=<0.001). Hypertensive patients (stage 2) had a higher risk of elevated pulse wave velocity than normotensive ones (adjPR=2.70, 95%CI: 1.05-6.95, p=0.040), as did patients younger than 12 years than the older patients (adjPR=2.95, 95%CI: 1.05-8.40, p=0.041). Hypertensive patients had a higher risk of elevated central systolic blood pressure than normotensives (adjPR=3.29, 95%Cl: 1.36-7.94), as did patients undergoing chronic dialysis treatment when comparing to nondialysis chronic kidney disease patients (adjPR=2.08, 95%Cl: 1.07-4.02). CONCLUSION: Younger age, dialysis, and hypertension in children are independently associated with higher pulse wave velocity. Hypertension and dialysis are independently associated with higher central systolic blood pressure.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Insuficiência Renal Crônica / Hipertensão Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Einstein (Sao Paulo) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Insuficiência Renal Crônica / Hipertensão Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Einstein (Sao Paulo) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil