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Influence of Weight Loss on Cognitive Functions: A Pilot Study of a Multidisciplinary Intervention Program for Obesity Treatment.
Chávez-Manzanera, Emma; Ramírez-Flores, Maura; Duran, Michelle; Torres, Mariana; Ramírez, Mariana; Kaufer-Horwitz, Martha; Stephano, Sylvana; Quiroz-Casian, Lizette; Cantú-Brito, Carlos; Chiquete, Erwin.
Afiliação
  • Chávez-Manzanera E; Obesity and Eating Disorders Clinic, Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.
  • Ramírez-Flores M; Laboratory of Neuropsychology and Cognition, School of Psychology, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
  • Duran M; Laboratory of Neuropsychology and Cognition, School of Psychology, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
  • Torres M; Laboratory of Neuropsychology and Cognition, School of Psychology, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
  • Ramírez M; Laboratory of Neuropsychology and Cognition, School of Psychology, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
  • Kaufer-Horwitz M; Obesity and Eating Disorders Clinic, Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.
  • Stephano S; Obesity and Eating Disorders Clinic, Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.
  • Quiroz-Casian L; Obesity and Eating Disorders Clinic, Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.
  • Cantú-Brito C; Department of Neurology and Psychiatry, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.
  • Chiquete E; Department of Neurology and Psychiatry, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.
Brain Sci ; 12(4)2022 Apr 17.
Article em En | MEDLINE | ID: mdl-35448040
There is a relationship between obesity and cognitive functioning. Our aim was to assess weight loss influence on global cognition and executive functioning (EF) in adults with obesity under a multidisciplinary weight loss program. In this six-month longitudinal study, we assessed 81 adults (age < 50 years) with body mass index (BMI) ≥ 30. EF and global cognitive performance were evaluated with the Montreal Cognitive Assessment (MoCA), Neuropsychological Battery of Executive Functions (BANFE-2) and Trail Making Test-Part B (TMT-B). Median age was 40.0 years (IQR: 31.5−47, 61% women), and the median BMI was 41.4 (IQR: 36.7−45.9). At a six-month follow-up, the mean weight loss was 2.67% (29.6% of patients achieved ≥5% weight loss). There was an improvement in EF evaluated with BANFE (p = 0.0024) and global cognition with MoCA (p = 0.0024). Women experienced more remarkable change, especially in EF. Weight loss did not correlate with cognitive performance, except for TMT-B (r-0.258, p = 0.026). In the regression analysis, only years of education predicted the MoCA score. This study showed that patients improved cognitive performance during the follow-up; nevertheless, the magnitude of weight loss did not correlate with cognitive improvement. Future studies are warranted to demonstrate if patients achieving ≥5% weight loss can improve cognition, secondary to weight loss.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Brain Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: México País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Brain Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: México País de publicação: Suíça