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A Titanium Tetrafluoride Experimental Gel Combined with Highly Concentrated Hydrogen Peroxide as an Alternative Bleaching Agent: An In Vitro Study.
Lins, Rodrigo; Rosalen, Pedro; Silva, Diego; Kawabata, Bianca; Martins, Luís Roberto; Cavalli, Vanessa.
Afiliação
  • Lins R; Department of Restorative Dentistry, Operative Dentistry Division, Piracicaba Dental School, University of Campinas, Avenida Limeira 901, Bairro Areião, Piracicaba 13414-903, SP, Brazil.
  • Rosalen P; Department of Pathology and Parasitology, Federal University of Alfenas, Rua Gabriel Monteiro da Silva, Centro, Alfenas 37130-001, MG, Brazil.
  • Silva D; Department of Biosciences, Piracicaba Dental School, University of Campinas, SP. Avenida Limeira 901, Bairro Areião, Piracicaba 13414-903, SP, Brazil.
  • Kawabata B; Research Program in Integrated Dental Sciences, University of Cuiabá, Cuiabá 78065-900, MG, Brazil.
  • Martins LR; Department of Restorative Dentistry, Operative Dentistry Division, Piracicaba Dental School, University of Campinas, Avenida Limeira 901, Bairro Areião, Piracicaba 13414-903, SP, Brazil.
  • Cavalli V; Department of Restorative Dentistry, Operative Dentistry Division, Piracicaba Dental School, University of Campinas, Avenida Limeira 901, Bairro Areião, Piracicaba 13414-903, SP, Brazil.
Gels ; 8(3)2022 Mar 14.
Article em En | MEDLINE | ID: mdl-35323291
This in vitro study evaluated color change, mineral content, and morphology of enamel, pH and cytotoxicity of experimental bleaching agents containing 35% hydrogen peroxide (HP), titanium tetrafluoride (TiF4), Natrosol, and Chemygel. Sixty enamel/dentin blocks were randomly treated with (n = 10) HP; HP+Natrosol+Chemygel with different TiF4 concentrations: 0.05 g HPT0.5, 0.1 g HPT1, 0.2 g HPT2, 0.3 g HPT3, 0.4 g HPT4. Bleaching was performed in three sessions (3 × 15 min application). Color change (CIELab-ΔEab, CIEDE2000-ΔE00, ΔWID) and Knoop microhardness (KHN) were evaluated. Enamel morphology and composition were observed under scanning electron microscopy and energy-dispersive spectrometry (EDS), respectively. Cell viability of keratinocyte cells was evaluated using MTT assay. Data were analyzed by one-way ANOVA and LSD and Tukey tests, and two-way repeated measures ANOVA and Bonferroni (α = 5%). The pH and EDS were analyzed descriptively. Lightness-L* increased, and a* and b* parameters decreased, except for HPT3 and HPT4 (b*). HPT0.5, HPT1, and HPT2 exhibited ΔEab and ΔWID similar to HP. ΔE00 did not present statistical difference. HP, HPT0.5, and HPT1 promoted higher KHN. HPT0.5 exhibited no changes on enamel surface. Keratinocyte cells were viable when treated with T0.5, and weak viable for T1. Experimental agents exhibited acidic pH and Ti elements. HPT0.5 exhibited bleaching efficacy, maintained KHN without enamel alterations, and did not increase cytotoxicity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Gels Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Gels Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça