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Risk Factors for Acute Kidney Injury and Death in Patients Infected With the Yellow Fever Virus During the 2018 Outbreak in São Paulo, Brazil.
Arantes, Márcia Fernanda; Seabra, Victor Faria; Lins, Paulo Ricardo Gessolo; Rodrigues, Camila Eleuterio; Reichert, Bernardo Vergara; Silveira, Marcelo Augusto Duarte; Li, Ho Yeh; Malbouisson, Luiz Marcelo; Andrade, Lúcia.
Afiliação
  • Arantes MF; Division of Nephrology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
  • Seabra VF; Division of Nephrology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
  • Lins PRG; Division of Nephrology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
  • Rodrigues CE; Division of Nephrology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
  • Reichert BV; Division of Nephrology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
  • Silveira MAD; Division of Nephrology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
  • Li HY; Intensive Care Unit, Department of Infectious and Parasitic Diseases, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
  • Malbouisson LM; Division of Anesthesiology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
  • Andrade L; Division of Nephrology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
Kidney Int Rep ; 7(3): 601-609, 2022 Mar.
Article em En | MEDLINE | ID: mdl-35257072
Introduction: There have been few studies investigating acute kidney injury (AKI) in patients with yellow fever (YF). The objective of this study was to identify the risk factors for AKI and death in such patients. Methods: We evaluated 95 consecutive critically ill adult patients with the sylvatic form of YF, as confirmed by reverse-transcriptase polymerase chain reaction, in Brazil. The outcome measures were AKI (as defined by Kidney Disease: Improving Global Outcomes [KDIGO] criteria) and in-hospital death. Results: Of the 95 patients, 73 (76.8%) had AKI and 59 (62.1%) died from it. A total of 70 patients (73.7%) required dialysis because of AKI. After adjusting for age, sex, and the Simplified Acute Physiology Score 3 (SAPS 3), we found that elevated fractional excretion of sodium and requiring dialysis were independent risk factors for in-hospital mortality and that proteinuria correlated with AKI-associated mortality. Conclusion: Our findings indicate that, in patients with sylvatic YF, AKI is common and is associated with significant mortality. The data presented here could prove useful for improving understanding of the pathogenesis of AKI in YF and informing decisions regarding the care of the affected patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies País/Região como assunto: America do sul / Brasil Idioma: En Revista: Kidney Int Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies País/Região como assunto: America do sul / Brasil Idioma: En Revista: Kidney Int Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos