Methylene blue for the treatment of refractory septic shock secondary to listeriosis in a paediatric patient.
BMJ Case Rep
; 15(2)2022 Feb 28.
Article
em En
| MEDLINE
| ID: mdl-35228212
Current therapies frequently used for refractory septic shock include hydrocortisone, vasopressin, extracorporeal membrane oxygenation (ECMO) support, inodilators, levosimendan and methylene blue. The evidence for these treatments is very limited. We present a case of a 5-year-old patient with refractory septic shock, secondary to Listeria monocytogenes meningitis. She presented with status epilepticus and developed septic shock. Shock persisted despite multiple high-dose vasoactive medications. ECMO support was not available. The medical team decided to use methylene blue to revert the vasoplegia, with excellent results. Shortly after the administration, vasopressors were weaned off and the high lactate cleared. She developed severe neurological sequelae due to brain haemorrhage secondary to the Listeria meningitis. The evidence supporting methylene blue for refractory septic shock in paediatric patients is limited. This case represents the effectiveness of this therapy without secondary effects.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Choque Séptico
/
Oxigenação por Membrana Extracorpórea
/
Listeriose
Limite:
Child
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Child, preschool
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Female
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Humans
Idioma:
En
Revista:
BMJ Case Rep
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Peru
País de publicação:
Reino Unido