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Methylene blue for the treatment of refractory septic shock secondary to listeriosis in a paediatric patient.
Domínguez-Rojas, Jesús Angel; Caqui, Patrick; Sanchez, Abel; Coronado Munoz, Alvaro J.
Afiliação
  • Domínguez-Rojas JA; Deparment of Pediatrics, National Hospital Edgardo Rebagliati Martins, Lima, Peru.
  • Caqui P; Deparment of Critical Care, Instituto Nacional De Salud Del Niño Breña, Lima, Peru.
  • Sanchez A; Department of Pediatrics, Hospital Nacional Hipolito Unanue, Lima, Peru.
  • Coronado Munoz AJ; Department of Pediatrics, Hospital Nacional Hipolito Unanue, Lima, Peru.
BMJ Case Rep ; 15(2)2022 Feb 28.
Article em En | MEDLINE | ID: mdl-35228212
Current therapies frequently used for refractory septic shock include hydrocortisone, vasopressin, extracorporeal membrane oxygenation (ECMO) support, inodilators, levosimendan and methylene blue. The evidence for these treatments is very limited. We present a case of a 5-year-old patient with refractory septic shock, secondary to Listeria monocytogenes meningitis. She presented with status epilepticus and developed septic shock. Shock persisted despite multiple high-dose vasoactive medications. ECMO support was not available. The medical team decided to use methylene blue to revert the vasoplegia, with excellent results. Shortly after the administration, vasopressors were weaned off and the high lactate cleared. She developed severe neurological sequelae due to brain haemorrhage secondary to the Listeria meningitis. The evidence supporting methylene blue for refractory septic shock in paediatric patients is limited. This case represents the effectiveness of this therapy without secondary effects.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Choque Séptico / Oxigenação por Membrana Extracorpórea / Listeriose Limite: Child / Child, preschool / Female / Humans Idioma: En Revista: BMJ Case Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Peru País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Choque Séptico / Oxigenação por Membrana Extracorpórea / Listeriose Limite: Child / Child, preschool / Female / Humans Idioma: En Revista: BMJ Case Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Peru País de publicação: Reino Unido