Autopsy in a Neonatal Intensive Care Unit: pathological and clinical agreement.

Penso, Camila; Corso, Andréa L; Hentges, Cláudia R; Silveira, Rita C; Rivero, Raquel C; Rojas, Bruna S; Tellechea, Tatiana S; Procianoy, Renato S

Penso, Camila; Corso, Andréa L; Hentges, Cláudia R; Silveira, Rita C; Rivero, Raquel C; Rojas, Bruna S; Tellechea, Tatiana S; Procianoy, Renato S.

Afiliação

Penso C; Hospital de Clínicas de Porto Alegre, Serviço de Neonatologia, Porto Alegre, RS, Brazil.
Corso AL; Hospital de Clínicas de Porto Alegre, Serviço de Neonatologia, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul, Departamento de Pediatria, Porto Alegre, RS, Brazil. Electronic address: alcorso@hcpa.edu.br.
Hentges CR; Hospital de Clínicas de Porto Alegre, Serviço de Neonatologia, Porto Alegre, RS, Brazil.
Silveira RC; Hospital de Clínicas de Porto Alegre, Serviço de Neonatologia, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul, Departamento de Pediatria, Porto Alegre, RS, Brazil.
Rivero RC; Hospital de Clínicas de Porto Alegre, Serviço de Neonatologia, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul, Departamento de Patologia, Porto Alegre, RS, Brazil.
Rojas BS; Hospital de Clínicas de Porto Alegre, Serviço de Neonatologia, Porto Alegre, RS, Brazil.
Tellechea TS; Hospital de Clínicas de Porto Alegre, Serviço de Neonatologia, Porto Alegre, RS, Brazil.
Procianoy RS; Hospital de Clínicas de Porto Alegre, Serviço de Neonatologia, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul, Departamento de Pediatria, Porto Alegre, RS, Brazil.

J Pediatr (Rio J) ; 98(5): 471-476, 2022.

Article em En | MEDLINE | ID: mdl-35189081

RESUMO

OBJECTIVES: To evaluate neonatal autopsy rates at a tertiary hospital in southern Brazil ascertain the level of agreement between premortem and postmortem diagnosis. METHODS: The authors reviewed all neonatal autopsies performed over a 10-year period and described the percentage of neonates who died and underwent autopsy. The authors tested for agreement between autopsy findings and the cause of death as defined by the neonatologist. Agreement between clinical diagnosis and autopsy findings was classified using the modified Goldman criteria. Additional findings at autopsy were grouped by organ system. Linear regression and multiple comparisons were used for statistical analyses. RESULTS: During the study period, 382 neonates died at the Neonatal Intensive Care Unit (NICU). Consent to perform an autopsy was obtained for 73 (19.1%). The complete agreement between autopsy findings and the neonatologist's premortem diagnosis was found in 48 patients (65.8%). Additional findings were obtained at autopsy in 25 cases (34.2%). In 5 cases (6.9%), the autopsy findings contributed to subsequent genetic counseling. Seven autopsies (9.6%) revealed a diagnosis that would have changed patient management if established premortem. The autopsy rate increased by an average of 1.87% each year. CONCLUSION: Despite a high level of agreement between clinical diagnosis and pathological findings, autopsies provided relevant data regarding the cause of death, providing additional clinical information to neonatologists and allowing genetic counseling of family members.

Assuntos

Unidades de Terapia Intensiva Neonatal; Autopsia; Brasil; Causas de Morte; Humanos; Recém-Nascido; Modelos Lineares; Estudos Retrospectivos

Palavras-chave

Autopsy; Cause of death; Necropsy; Neonate

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Unidades de Terapia Intensiva Neonatal Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans / Newborn País/Região como assunto: America do sul / Brasil Idioma: En Revista: J Pediatr (Rio J) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google