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Seasonal Chemical Evaluation of Miconia chamissois Naudin from Brazilian Savanna.
Ferreira, Juliana de Freitas; López, Manuel Humberto Mera; Gomes, João Victor Dutra; Martins, Diegue H Nascimento; Fagg, Christopher William; Magalhães, Pérola Oliveira; Davies, Noel William; Silveira, Dâmaris; Fonseca-Bazzo, Yris Maria.
Afiliação
  • Ferreira JF; Department of Pharmacy, Health Sciences School, University of Brasília, Brasilia 70910-900, Brazil.
  • López MHM; Department of Pharmacy, Health Sciences School, University of Brasília, Brasilia 70910-900, Brazil.
  • Gomes JVD; Department of Pharmacy, Health Sciences School, University of Brasília, Brasilia 70910-900, Brazil.
  • Martins DHN; Department of Pharmacy, Health Sciences School, University of Brasília, Brasilia 70910-900, Brazil.
  • Fagg CW; Department of Botany, Institute of Biological Science, Ceilândia Campus, School of Pharmacy, University of Brasília, Brasilia 70910-900, Brazil.
  • Magalhães PO; Department of Pharmacy, Health Sciences School, University of Brasília, Brasilia 70910-900, Brazil.
  • Davies NW; Central Science Laboratory, University of Tasmania, Hobart, TAS 7005, Australia.
  • Silveira D; Department of Pharmacy, Health Sciences School, University of Brasília, Brasilia 70910-900, Brazil.
  • Fonseca-Bazzo YM; Department of Pharmacy, Health Sciences School, University of Brasília, Brasilia 70910-900, Brazil.
Molecules ; 27(3)2022 Feb 08.
Article em En | MEDLINE | ID: mdl-35164385
Miconia chamissois Naudin is a species from the Cerrado, which is being increasingly researched for its therapeutic potential. The aim of this study was to obtain a standardized extract and to evaluate seasonal chemical variations. Seven batches of aqueous extracts from leaves were produced for the standardization. These extracts were evaluated for total solids, polyphenol (TPC) and flavonoid content (TFC), vitexin derivative content, antioxidant activity; thin-layer chromatography (TLC), and high-performance liquid chromatography (HPLC) profiles were generated. For the seasonal study, leaves were collected from five different periods (May 2017 to August 2018). The results were correlated with meteorological data (global radiation, temperature, and rainfall index). Using chromatographic and spectroscopic techniques, apigenin C-glycosides (vitexin/isovitexin) and derivatives, luteolin C-glycosides (orientin/isoorientin) and derivatives, a quercetin glycoside, miconioside B, matteucinol-7-O-ß-apiofuranosyl (1 → 6) -ß-glucopyranoside, and farrerol were identified. Quality parameters, including chemical marker quantification by HPLC, and biological activity, are described. In the extract standardization process, all the evaluated parameters showed low variability. The seasonality study revealed no significant correlations (p < 0.05) between TPC or TFC content and meteorological data. These results showed that it is possible to obtain extracts from M. chamissois at any time of the year without significant differences in composition.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Folhas de Planta / Melastomataceae País/Região como assunto: America do sul / Brasil Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Folhas de Planta / Melastomataceae País/Região como assunto: America do sul / Brasil Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça