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The Therapeutic Potential of Psychedelic-assisted Therapies for Symptom Control in Patients Diagnosed With Serious Illness: A Systematic Review.
Maia, Lucas Oliveira; Beaussant, Yvan; Garcia, Ana Cláudia Mesquita.
Afiliação
  • Maia LO; Interdisciplinary Center for Studies in Palliative Care (L.O.M., A.C.M.G.), School of Nursing, Federal University of Alfenas, Alfenas, Minas Gerais, Brazil; Interdisciplinary Cooperation for Ayahuasca Research and Outreach (ICARO) (L.O.M.), School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil.
  • Beaussant Y; Department of Psychosocial Oncology and Palliative Care (Y.B.), Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Garcia ACM; Interdisciplinary Center for Studies in Palliative Care (L.O.M., A.C.M.G.), School of Nursing, Federal University of Alfenas, Alfenas, Minas Gerais, Brazil. Electronic address: ana.mesquita@unifal-mg.edu.br.
J Pain Symptom Manage ; 63(6): e725-e738, 2022 06.
Article em En | MEDLINE | ID: mdl-35157985
CONTEXT: People affected by serious illness usually experience suffering in its various dimensions, not only in the physical but also in the psychosocial and spiritual aspects. The interest in psychedelic-assisted therapies as a potential new therapeutic modality has increased since evidence suggests a significant impact of their use on the outcomes of patients with serious illness. OBJECTIVES: To systematically review the available evidence on the effects of psychedelic-assisted therapies for symptom control in patients diagnosed with serious illness. METHODS: The protocol of this systematic review has been prepared according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines. This review included randomized and non-randomized controlled trials published in peer-reviewed scientific journals. A comprehensive search for studies was carried out in the main scientific databases, including Web of Science, Scopus, Cochrane Library, PsycINFO, PubMed, CINAHL, and EMBASE. There were no limitations regarding the year or language of publication. RESULTS: The sample was composed of 20 studies. The results suggest positive effects of psychedelic-assisted therapies for symptom control in patients diagnosed with serious illness, with considerable safety of use. Most studies have been conducted with lysergic acid diethylamide, psilocybin, and N,N-dipropyltryptamine in cancer patients. The adverse effects reported were of physical and/or psychological nature and of mild to moderate intensity, transient, and self-resolutive. CONCLUSION: The evaluated evidence suggests positive effects of psychedelic-assisted therapies for symptom control in patients diagnosed with serious illness, especially regarding symptoms of psychological and spiritual nature.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alucinógenos Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Systematic_reviews Limite: Humans Idioma: En Revista: J Pain Symptom Manage Assunto da revista: NEUROLOGIA / PSICOFISIOLOGIA / TERAPEUTICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alucinógenos Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Systematic_reviews Limite: Humans Idioma: En Revista: J Pain Symptom Manage Assunto da revista: NEUROLOGIA / PSICOFISIOLOGIA / TERAPEUTICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos