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Therapeutic Applications of Curcumin in Diabetes: A Review and Perspective.
Quispe, Cristina; Herrera-Bravo, Jesús; Javed, Zeeshan; Khan, Khushbukhat; Raza, Shahid; Gulsunoglu-Konuskan, Zehra; Dastan, Sevgi Durna; Sytar, Oksana; Martorell, Miquel; Sharifi-Rad, Javad; Calina, Daniela.
Afiliação
  • Quispe C; Facultad de Ciencias de la Salud, Universidad Arturo Prat, Avda Arturo Prat 2120, Iquique 1110939, Chile.
  • Herrera-Bravo J; Departamento de Ciencias Básicas, Facultad de Ciencias, Universidad Santo Tomas, Chile.
  • Javed Z; Center of Molecular Biology and Pharmacogenetics, Scientific and Technological Bioresource Nucleus, Universidad de La Frontera, Temuco 4811230, Chile.
  • Khan K; Office for Research Innovation and Commercialization, Lahore Garrison University, Lahore, Pakistan.
  • Raza S; Atta-ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, Punjab, Pakistan.
  • Gulsunoglu-Konuskan Z; Office for Research Innovation and Commercialization, Lahore Garrison University, Lahore, Pakistan.
  • Dastan SD; Faculty of Health Science, Nutrition and Dietetics Department, Istanbul Aydin University, Istanbul 34295, Turkey.
  • Sytar O; Department of Biology, Faculty of Science, Sivas Cumhuriyet University, 58140 Sivas, Turkey.
  • Martorell M; Beekeeping Development Application and Research Center, Sivas Cumhuriyet University, 58140 Sivas, Turkey.
  • Sharifi-Rad J; Department of Plant Physiology, Slovak University of Agriculture, A. Hlinku 2, 94976 Nitra, Slovakia.
  • Calina D; Department of Plant Biology, Institute of Biology, Kiev National, University of Taras Shevchenko, Volodymyrska, 64, 01033 Kyiv, Ukraine.
Biomed Res Int ; 2022: 1375892, 2022.
Article em En | MEDLINE | ID: mdl-35155670
Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug therapy as well as lifestyle changes. There is now growing scientific evidence to support the effectiveness of the use of herbal supplements in the prevention and control of diabetes. Curcumin is one of the most studied bioactive components of traditional medicine, but its physicochemical characteristics are represented by low solubility, poor absorption, and low efficacy. Nanotechnology-based pharmaceutical formulations can help overcome the problems of reduced bioavailability of curcumin and increase its antidiabetic effects. The objectives of this review were to review the effects of nanocurcumin on DM and to search for databases such as PubMed/MEDLINE and ScienceDirect. The results showed that the antidiabetic activity of nanocurcumin is due to complex pharmacological mechanisms by reducing the characteristic hyperglycemia of DM. In light of these results, nanocurcumin may be considered as potential agent in the pharmacotherapeutic management of patients with diabetes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Curcumina / Nanotecnologia / Diabetes Mellitus Limite: Humans Idioma: En Revista: Biomed Res Int Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Chile País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Curcumina / Nanotecnologia / Diabetes Mellitus Limite: Humans Idioma: En Revista: Biomed Res Int Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Chile País de publicação: Estados Unidos