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Polymeric Nanoparticles for the Treatment of Prostate Cancer- Technological Prospecting and Critical Analysis.
de Oliveira, Clauberto Rodrigues; Droppa-Almeida, Daniela; Padilha, Francine Ferreira; de Souza, Roberto Rodrigues; de Albuquerque-Júnior, Ricardo Luiz Cavalcanti.
Afiliação
  • de Oliveira CR; Department of Environmental Health, Universidade Tiradentes, Aracaju-Sergipe, Brazil.
  • Droppa-Almeida D; Department of Industrial Biotechnology, Universidade Tiradentes, Instituto de Tecnologia e Pesquisa -Avenida Murilo Dantas, 300, Bairro Farolândia, Aracaju-Sergipe, Brazil.
  • Padilha FF; Universidade Tiradentes Postgraduate Program in Health and Environment, Universidade Tiradentes, Aracaju-Sergipe, Brazil.
  • de Souza RR; Departamento de Engenharia Química; Universidade Federal de Sergipe; Av. Marechal Rondom, S/N; 49100-000, Aracaju - SE - Brasil.
  • de Albuquerque-Júnior RLC; Instituto de Tecnologia e Pesquisa, Universidade Tiradentes, Aracaju-Sergipe, Brazil.
Recent Pat Nanotechnol ; 17(1): 8-14, 2023.
Article em En | MEDLINE | ID: mdl-35100962
BACKGROUND: Polymeric nanoparticles have a wide diversity, and due to their toxicity and biodegradability, they have been widely used in the health area. Its use allows stability of some compounds, targeted delivery, and increased half-life, in this context, making some treatment proposals more effective. Prostate cancer, in turn, is among the types of cancer with the highest mortality, and the lack of effective treatment causes several strategies to meet this need. OBJECTIVE: The objective of this work was to verify patents that use polymeric nanoparticles for the treatment of prostate cancer. METHODS: For that, specific keywords to direct the search were applied in Patent Scope. After obtaining the patents, one was selected for the development of critical analysis in relation to its chemistry and biology. RESULTS: A total of five patents were found and, of these, an invention that used PCL-PLGA-PEGCOOH polymeric nanoparticles with two natural compounds, resveratrol and celastrol, providing an alternative method to traditional monotherapies. CONCLUSION: The prospective analysis serves to direct us in relation to the technologies currently used in certain fields. Based on several cases of cancer and specifically the countless cases of prostate cancer, five recent patents were found using polymeric nanoparticles. However, only one brought a different aspect of all the treatments used lately. It brought an invention containing two natural compounds being carried with polymeric nanoparticles with promising results.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Nanopartículas Limite: Humans / Male Idioma: En Revista: Recent Pat Nanotechnol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Emirados Árabes Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Nanopartículas Limite: Humans / Male Idioma: En Revista: Recent Pat Nanotechnol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Emirados Árabes Unidos