Lactose-binding lectin from Vatairea macrocarpa seeds induces in vivo angiogenesis via VEGF and TNF-É expression and modulates in vitro doxorubicin-induced genotoxicity.

Véras, Jefferson Hollanda; Cardoso, Clever Gomes; Puga, Sara Cristina; de Melo Bisneto, Abel Vieira; Roma, Renato Rodrigues; Santos Silva, Romerio Rodrigues; Teixeira, Claudener Souza; Chen-Chen, Lee

Lactose-binding lectin from Vatairea macrocarpa seeds induces in vivo angiogenesis via VEGF and TNF-É expression and modulates in vitro doxorubicin-induced genotoxicity.

Véras, Jefferson Hollanda; Cardoso, Clever Gomes; Puga, Sara Cristina; de Melo Bisneto, Abel Vieira; Roma, Renato Rodrigues; Santos Silva, Romerio Rodrigues; Teixeira, Claudener Souza; Chen-Chen, Lee.

Afiliação

Véras JH; Laboratory of Radiobiology and Mutagenesis, Institute of Biological Sciences, Federal University of Goiás, Goiânia, GO, Brazil.
Cardoso CG; Laboratory of Radiobiology and Mutagenesis, Institute of Biological Sciences, Federal University of Goiás, Goiânia, GO, Brazil.
Puga SC; Laboratory of Radiobiology and Mutagenesis, Institute of Biological Sciences, Federal University of Goiás, Goiânia, GO, Brazil.
de Melo Bisneto AV; Laboratory of Radiobiology and Mutagenesis, Institute of Biological Sciences, Federal University of Goiás, Goiânia, GO, Brazil.
Roma RR; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, CE, Brazil.
Santos Silva RR; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, CE, Brazil.
Teixeira CS; Center of Agrarian Science and Biodiversity, Federal University of Cariri, Crato, CE, Brazil.
Chen-Chen L; Laboratory of Radiobiology and Mutagenesis, Institute of Biological Sciences, Federal University of Goiás, Goiânia, GO, Brazil. Electronic address: chenleego@yahoo.com.br.

Biochimie ; 194: 55-66, 2022 Mar.

Article em En | MEDLINE | ID: mdl-34973362

Assuntos

Lectinas; Fator A de Crescimento do Endotélio Vascular; Animais; Embrião de Galinha; Dano ao DNA; Doxorrubicina/farmacologia; Humanos; Lactose/farmacologia; Lectinas/metabolismo; Neovascularização Fisiológica; Sementes/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Angiogenesis; CAM assay; CometChip; Genotoxicity; Immunohistochemistry; Vatairea macrocarpa lectin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator A de Crescimento do Endotélio Vascular / Lectinas Limite: Animals / Humans Idioma: En Revista: Biochimie Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: França

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