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Natriuretic peptides to differentiate constrictive pericarditis and restrictive cardiomyopathy: A systematic review and meta-analysis.
Diaz-Arocutipa, Carlos; Saucedo-Chinchay, Jose; Imazio, Massimo; Argulian, Edgar.
Afiliação
  • Diaz-Arocutipa C; Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima, Peru.
  • Saucedo-Chinchay J; Programa de Atención Domiciliaria, EsSalud, Lima, Peru.
  • Imazio M; Asociación para el Desarrollo de la Investigación Estudiantil en Ciencias de la Salud (ADIECS), Lima, Peru.
  • Argulian E; Department of Emergency, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru.
Clin Cardiol ; 45(3): 251-257, 2022 Mar.
Article em En | MEDLINE | ID: mdl-34967020
Previous studies have shown that natriuretic peptide levels are increased in patients with restrictive cardiomyopathy (RCM) but not in constrictive pericarditis (CP). We performed a systematic review and meta-analysis to evaluate the diagnostic utility of B-type natriuretic peptide (BNP) and N-terminal pro-brain natriuretic peptide (NT-proBNP) to differentiate CP and RCM. We searched electronic databases from inception to January 07, 2021. Studies involving adult patients that assessed the utility of natriuretic peptides to differentiate CP and RCM were included. All meta-analyses were performed using a random-effects model. Seven studies (four case-control and three cohorts) involving 204 patients were included. The mean age ranged between 25.7 and 64.1 years and 77% of patients were men. BNP levels were significantly lower (standardized median difference [SMD], -1.48; 95% confidence interval [CI], -2.33 to -0.63) in patients with CP compared to RCM. The pooled area under the curve (AUC) of the BNP level was 0.81 (95% CI, 0.70-0.92). NT-proBNP (SMD, -0.86; 95% CI, -1.38 to -0.33) and log NT-proBNP (SMD, -1.89; 95% CI, -2.59 to -1.20) levels were significantly lower in patients with CP compared to RCM. Our review shows that BNP and NT-proBNP levels were significantly lower in patients with CP compared to RCM. The pooled AUC of BNP level showed a good diagnostic accuracy to differentiate both conditions.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pericardite Constritiva / Cardiomiopatia Restritiva Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Systematic_reviews Limite: Adult / Humans / Male / Middle aged Idioma: En Revista: Clin Cardiol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Peru País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pericardite Constritiva / Cardiomiopatia Restritiva Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Systematic_reviews Limite: Adult / Humans / Male / Middle aged Idioma: En Revista: Clin Cardiol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Peru País de publicação: Estados Unidos