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One-Anastomosis and Roux-en-Y Gastric Bypass Promote Similar Weight Loss, Patient Satisfaction, Quality of Life, Inflammation Grade, and Cellular Damage in the Esophagus and Gastric Pouch in a Short-term Follow-up.
Katayama, Rafael C; Arasaki, Carlos H; Herbella, Fernando A M; Neto, Ricardo A; Lopes Filho, Gaspar de Jesus.
Afiliação
  • Katayama RC; Department of Surgery, Division of Surgical Gastroenterology, Universidade Federal de São Paulo-UNIFESP, São Paulo, Brazil.
  • Arasaki CH; Department of Surgery, Division of Surgical Gastroenterology, Universidade Federal de São Paulo-UNIFESP, São Paulo, Brazil.
  • Herbella FAM; Department of Pathology, Escola Paulista de Medicina-EPM, São Paulo, Brazil.
  • Neto RA; Department of Pathology, Escola Paulista de Medicina-EPM, São Paulo, Brazil.
  • Lopes Filho GJ; Department of Surgery, Division of Surgical Gastroenterology, Universidade Federal de São Paulo-UNIFESP, São Paulo, Brazil.
J Obes Metab Syndr ; 30(4): 396-402, 2021 12 30.
Article em En | MEDLINE | ID: mdl-34903679
Background: One-anastomosis gastric bypass (OAGB) is a simpler procedure than Roux-en-Y gastric bypass (RYGB); however, biliary reflux can occur and impair outcomes. This study aimed to compare outcomes of OAGB and RYGB. Methods: Twenty patients with morbid obesity were randomized prospectively into two groups: OAGB (n=10) or RYGB (n=10). Quality of life (36-item short-form health survey [SF-36]), satisfaction (Visick scale), and body mass index (BMI) were evaluated before and 6 months after the operation. All patients underwent esophagogastroduodenoscopy with gastric and esophageal mucosal biopsies at 3 and 6 months after their operation. Results: The study found no significant difference in BMI before surgery (OAGB, 43.2 kg/m2; RYGB, 43.1 kg/m2; P=0.90) or at 6 months postoperative (OAGB, 32.1 kg/m2; RYGB, 31.8 kg/m2; P=0.91). There was no significant difference in improvement of quality of life (four SF-36 domains) or satisfaction (P=0.08) between groups at 6 months. There was no statistical difference between gastric (P=0.10) and esophageal (P=0.76) inflammation grade at three or 6 months between the two groups. Conclusion: OAGB and RYGB are equally effective in terms of weight loss, patient satisfaction, and quality of life improvement at 6 months after the procedures. Inflammation grade and cellular damage in the gastric pouch and in the esophagus were similar.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Aspecto: Patient_preference Idioma: En Revista: J Obes Metab Syndr Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação:
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Aspecto: Patient_preference Idioma: En Revista: J Obes Metab Syndr Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: