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Novel Adiposity and Biochemical-Anthropometric Indices to Identify Cardiometabolic Risk and Metabolic Syndrome in Mexican Adults.
Rodríguez-Carrillo, Patricia Lizett; Aguirre-Tostado, Priscila Irene; Macías-Cervantes, Maciste H; Alegría-Torres, Jorge Alejandro; Luevano-Contreras, Claudia.
Afiliação
  • Rodríguez-Carrillo PL; Department of Medical Sciences, University of Guanajuato, León 37320, Mexico.
  • Aguirre-Tostado PI; Department of Medical Sciences, University of Guanajuato, León 37320, Mexico.
  • Macías-Cervantes MH; Department of Medical Sciences, University of Guanajuato, León 37320, Mexico.
  • Alegría-Torres JA; Department of Pharmacy, University of Guanajuato, Guanajuato 36000, Mexico.
  • Luevano-Contreras C; Department of Medical Sciences, University of Guanajuato, León 37320, Mexico.
Healthcare (Basel) ; 9(11)2021 Nov 16.
Article em En | MEDLINE | ID: mdl-34828607
Although several indices used in clinical practice identify cardiometabolic risk (CR) and metabolic syndrome (MetS), it is imperative to develop indices for specific populations. Therefore, we proposed and validated sex-specific indices to identify CR associated with visceral adipose tissue (VAT) accumulation or MetS in Mexican adults. Additionally, a cut-off value for the visceral fat area (VFA) to identify CR was proposed. Clinical, anthropometric, biochemical, and body composition variables were evaluated in 904 subjects (25-45 years old) (84.4% men). Multiple and logistic regressions were used to model the indices and ROC curve analysis to determine predictive performance. An additional cohort (n = 186) was used for indices validation, and Cohen's kappa coefficient was employed for agreement analysis. The proposed sex-specific indices, called Mexican adiposity indices (MAIs) and biochemical-anthropometric indices (BAIs), were good predictors for CR and MetS. The kappa coefficients showed a moderate agreement level. The VFA cut-off value chosen to identify CR was 100.3 cm2 because it had the best combination of sensitivity (66.8%) and specificity (64.4%). MAIs and BAIs could be clinical tools to identify either CR associated to VAT accumulation or MetS, respectively. A VFA cut-off value of 100.3 cm2 could identify CR in Mexican men.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies País/Região como assunto: Mexico Idioma: En Revista: Healthcare (Basel) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: México País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies País/Região como assunto: Mexico Idioma: En Revista: Healthcare (Basel) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: México País de publicação: Suíça