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Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study.
Reinke, Stacey N; Naz, Shama; Chaleckis, Romanas; Gallart-Ayala, Hector; Kolmert, Johan; Kermani, Nazanin Z; Tiotiu, Angelica; Broadhurst, David I; Lundqvist, Anders; Olsson, Henric; Ström, Marika; Wheelock, Åsa M; Gómez, Cristina; Ericsson, Magnus; Sousa, Ana R; Riley, John H; Bates, Stewart; Scholfield, James; Loza, Matthew; Baribaud, Frédéric; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; Fowler, Stephen J; Geiser, Thomas; Howarth, Peter; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Behndig, Annelie; Singer, Florian; Musial, Jacek; Shaw, Dominick E; Dahlén, Barbro; Hu, Sile; Lasky-Su, Jessica; Sterk, Peter J; Chung, Kian Fan; Djukanovic, Ratko; Dahlén, Sven-Erik; Adcock, Ian M; Wheelock, Craig E.
Afiliação
  • Reinke SN; Division of Physiological Chemistry 2, Dept of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
  • Naz S; Centre for Integrative Metabolomics and Computational Biology, School of Science, Edith Cowan University, Perth, Australia.
  • Chaleckis R; Equal contribution.
  • Gallart-Ayala H; Division of Physiological Chemistry 2, Dept of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
  • Kolmert J; Equal contribution.
  • Kermani NZ; Division of Physiological Chemistry 2, Dept of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
  • Tiotiu A; Gunma Initiative for Advanced Research (GIAR), Gunma University, Maebashi, Japan.
  • Broadhurst DI; Division of Physiological Chemistry 2, Dept of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
  • Lundqvist A; Division of Physiological Chemistry 2, Dept of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
  • Olsson H; The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Ström M; National Heart and Lung Institute, Imperial College, London, UK.
  • Wheelock ÅM; National Heart and Lung Institute, Imperial College, London, UK.
  • Gómez C; Dept of Pulmonology, University Hospital of Nancy, Nancy, France.
  • Ericsson M; Centre for Integrative Metabolomics and Computational Biology, School of Science, Edith Cowan University, Perth, Australia.
  • Sousa AR; DMPK, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Riley JH; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Bates S; Respiratory Medicine Unit, K2 Dept of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Scholfield J; Dept of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.
  • Loza M; Respiratory Medicine Unit, K2 Dept of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Baribaud F; Dept of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.
  • Bakke PS; Division of Physiological Chemistry 2, Dept of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
  • Caruso M; The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Chanez P; Dept of Clinical Pharmacology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
  • Fowler SJ; GlaxoSmithKline, London, UK.
  • Geiser T; GlaxoSmithKline, London, UK.
  • Howarth P; GlaxoSmithKline, London, UK.
  • Horváth I; Faculty of Medicine, Southampton University and NIHR Southampton Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.
  • Krug N; Janssen Research and Development, High Wycombe, UK.
  • Montuschi P; Janssen Research and Development, High Wycombe, UK.
  • Behndig A; Institute of Medicine, University of Bergen, Bergen, Norway.
  • Singer F; Dept of Biomedical and Biotechnological Sciences and Dept of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
  • Musial J; Assistance Publique des Hôpitaux de Marseille, Clinique des Bronches, Allergies et Sommeil, Aix Marseille Université, Marseille, France.
  • Shaw DE; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, and Manchester Academic Health Science Centre and NIHR Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manches
  • Dahlén B; Dept of Pulmonary Medicine, University Hospital, University of Bern, Bern, Switzerland.
  • Hu S; Faculty of Medicine, Southampton University and NIHR Southampton Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.
  • Lasky-Su J; Dept of Pulmonology, Semmelweis University, Budapest, Hungary.
  • Sterk PJ; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.
  • Chung KF; Pharmacology, Catholic University of the Sacred Heart, Rome, Italy.
  • Djukanovic R; Dept of Public Health and Clinical Medicine, Section of Medicine, Umeå University, Umeå, Sweden.
  • Dahlén SE; Division of Paediatric Respiratory Medicine and Allergology, Dept of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
  • Adcock IM; Dept of Medicine, Jagiellonian University Medical College, Krakow, Poland.
  • Wheelock CE; Nottingham NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Eur Respir J ; 59(6)2022 06.
Article em En | MEDLINE | ID: mdl-34824054
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Antiasmáticos Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Eur Respir J Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suécia País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Antiasmáticos Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Eur Respir J Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suécia País de publicação: Reino Unido