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[Paracetamol as an adjuvant to opioids for cancer pain management]. / Paracetamol como coadyuvante a opioides fuertes en dolor oncológico moderado a intenso: ¿es realmente efectivo?
vLeiva-Vásquez, Ofelia; Pérez-Cruz, Pedro.
Afiliação
  • vLeiva-Vásquez O; Departamento de Medicina Interna, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Pérez-Cruz P; Departamento de Medicina Interna, Pontificia Universidad Católica de Chile, Santiago, Chile.
Rev Med Chil ; 149(6): 899-905, 2021 Jun.
Article em Es | MEDLINE | ID: mdl-34751349
Cancer related pain is one of the most frequent and relevant symptoms in patients with malignant tumors, causing a huge impact in their quality of life. According to the Chilean Public Health System Technical Report of the Cancer Pain Control and Palliative Care Program 2013-2014, 90% of cancer patients admitted to the Program experienced pain, being moderate or intense in 34%. International and local standards recommend the use of strong opioids (morphine, methadone, or fentanyl) associated with adjuvants such as paracetamol as an initial strategy for pain management. This recommendation assumes that the use of combined analgesics could allow the use of lower opioid doses to obtain similar analgesic effect, decreasing the occurrence of opioid side effects. However, this technical report also describes that there is uncertainty about the impact of paracetamol as an adjuvant in patients with cancer pain who are already receiving strong opioids. This review aims to describe the current state of the art regarding the role of paracetamol as a coadjuvant in cancer pain patients.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Analgésicos Opioides / Neoplasias Aspecto: Patient_preference Limite: Humans Idioma: Es Revista: Rev Med Chil Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Chile País de publicação: Chile

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Analgésicos Opioides / Neoplasias Aspecto: Patient_preference Limite: Humans Idioma: Es Revista: Rev Med Chil Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Chile País de publicação: Chile