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Scaffold biomaterials and nano-based therapeutic strategies for skeletal muscle regeneration.
Tacchi, Franco; Orozco-Aguilar, Josué; Gutiérrez, Danae; Simon, Felipe; Salazar, Javier; Vilos, Cristian; Cabello-Verrugio, Claudio.
Afiliação
  • Tacchi F; Department of Biological Sciences, Laboratory of Muscle Pathology, Fragility & Aging, Faculty of Life Sciences, Universidad Andres Bello, Santiago, 8370146, Chile.
  • Orozco-Aguilar J; Millennium Institute on Immunology & Immunotherapy, Santiago, 8370146, Chile.
  • Gutiérrez D; Center for The Development of Nanoscience & Nanotechnology (CEDENNA), Universidad de Santiago de Chile, Santiago, 8350709, Chile.
  • Simon F; Department of Biological Sciences, Laboratory of Muscle Pathology, Fragility & Aging, Faculty of Life Sciences, Universidad Andres Bello, Santiago, 8370146, Chile.
  • Salazar J; Millennium Institute on Immunology & Immunotherapy, Santiago, 8370146, Chile.
  • Vilos C; Center for The Development of Nanoscience & Nanotechnology (CEDENNA), Universidad de Santiago de Chile, Santiago, 8350709, Chile.
  • Cabello-Verrugio C; Department of Biological Sciences, Laboratory of Muscle Pathology, Fragility & Aging, Faculty of Life Sciences, Universidad Andres Bello, Santiago, 8370146, Chile.
Nanomedicine (Lond) ; 16(28): 2521-2538, 2021 12.
Article em En | MEDLINE | ID: mdl-34743611
Skeletal muscle is integral to the functioning of the human body. Several pathological conditions, such as trauma (primary lesion) or genetic diseases such as Duchenne muscular dystrophy (DMD), can affect and impair its functions or exceed its regeneration capacity. Tissue engineering (TE) based on natural, synthetic and hybrid biomaterials provides a robust platform for developing scaffolds that promote skeletal muscle regeneration, strength recovery, vascularization and innervation. Recent 3D-cell printing technology and the use of nanocarriers for the release of drugs, peptides and antisense oligonucleotides support unique therapeutic alternatives. Here, the authors present recent advances in scaffold biomaterials and nano-based therapeutic strategies for skeletal muscle regeneration and perspectives for future endeavors.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Materiais Biocompatíveis / Alicerces Teciduais Limite: Humans Idioma: En Revista: Nanomedicine (Lond) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Chile País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Materiais Biocompatíveis / Alicerces Teciduais Limite: Humans Idioma: En Revista: Nanomedicine (Lond) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Chile País de publicação: Reino Unido