Your browser doesn't support javascript.
loading
Comparison between different prognostic models to be used for metastatic bone disease on appendicular skeleton in a Chilean population.
Alfaro, Patricio A; Delgado, Javier; Dumas, Andrés; Mesa, Cecilia; Wevar, Orlando; Herrera, Carlos; Padilla, Fabian; Botello, Eduardo.
Afiliação
  • Alfaro PA; Hospital Traumatológico de Concepción, Faculty of Medicine, Universidad de Concepción, San Martin 1580, Concepción, Chile. patricioalfaro@udec.cl.
  • Delgado J; Hospital Base de Valdivia, Faculty of Medicine, Universidad Austral, Valdivia, Chile.
  • Dumas A; Orthopedic Oncology Department, Instituto Traumatológico, Santiago, Chile.
  • Mesa C; Faculty of Medicine, Universidad Católica del Maule, Talca, Chile.
  • Wevar O; Orthopedic Oncology Department, Instituto Traumatológico, Santiago, Chile.
  • Herrera C; Hospital Traumatológico de Concepción, Faculty of Medicine, Universidad de Concepción, San Martin 1580, Concepción, Chile.
  • Padilla F; Hospital Traumatológico de Concepción, Faculty of Medicine, Universidad de Concepción, San Martin 1580, Concepción, Chile.
  • Botello E; Hospital Clínico Universidad Católica, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Eur J Orthop Surg Traumatol ; 31(8): 1657-1662, 2021 Dec.
Article em En | MEDLINE | ID: mdl-34677661
PURPOSE: Several preoperation prognosis models used on the treatment of metastatic bone disease on appendicular skeleton have been devised. The purpose of this study was to compare the performance of different survival prognostic models on patients with metastatic bone disease in long bones in a Chilean population. METHODS: This is a multicentric retrospective study. We retrospectively reviewed the medical records of 136 patients who were confirmed with metastatic bone disease of the appendicular skeleton and who were treated surgically from 2016 to 2019. The minimum follow-up time was 12 months. All patients were assessed using four appendicular metastatic bone disease scoring systems. A preoperative predicted survival time for all 136 patients was retrospectively calculated making use of the revised Katagiri, PathFx, Optimodel and IOR score model. RESULTS: The PathFx model demonstrated an accuracy at predicting 3 (area under the curve [AUC] = 0.61) and 6-month (AUC = 0.65) survival time after surgical management. IOR score model demonstrated an accuracy at predicting 12-month survival time (AUC = 0.64). The survival rate reached the 44% in a year. The median survival time to death or last follow-up time was 14.9 months (SD ± 15). CONCLUSION: PathFx score model demonstrated the highest accuracy at predicting a survival time of 3 and 6 months. IOR score model was the most accurate measure at predicting a survival time of 12-months. To our knowledge, this is the first study reporting a comparative analysis of metastatic bone disease with predicting models in a country located in Latin America. PathFx's and IOR score models are the ones to be used in the Chilean population as the predictive models in metastatic bone disease of the appendicular skeleton.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: America do sul / Chile Idioma: En Revista: Eur J Orthop Surg Traumatol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Chile País de publicação: França
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: America do sul / Chile Idioma: En Revista: Eur J Orthop Surg Traumatol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Chile País de publicação: França