Your browser doesn't support javascript.
loading
Relationship of Purpose in Life to Dementia in Older Black and White Brazilians.
Wilson, Robert S; Capuano, Ana W; Sampaio, Carolina; Leurgans, Sue E; Barnes, Lisa L; Boyle, Patricia A; Farfel, Jose M; Bennett, David A.
Afiliação
  • Wilson RS; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
  • Capuano AW; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
  • Sampaio C; Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.
  • Leurgans SE; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
  • Barnes LL; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
  • Boyle PA; Instituto de Assistencia Medica ao Servidor Publico do Estado (IAMSPE), Sao Paulo, Brazil.
  • Farfel JM; Instituto de Assistencia Medica ao Servidor Publico do Estado (IAMSPE), Sao Paulo, Brazil.
  • Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
J Int Neuropsychol Soc ; 28(10): 997-1002, 2022 11.
Article em En | MEDLINE | ID: mdl-34663484
OBJECTIVES: To test the hypothesis that higher level of purpose in life is associated with lower likelihood of dementia and mild cognitive impairment (MCI) in older Brazilians. METHODS: As part of the Pathology, Alzheimer's and Related Dementias Study (PARDoS), informants of 1,514 older deceased Brazilians underwent a uniform structured interview. The informant interview included demographic data, the Clinical Dementia Rating scale to diagnose dementia and MCI, the National Institute of Mental Health Diagnostic Interview Schedule for depression, and a 6-item measure of purpose in life, a component of well-being. RESULTS: Purpose scores ranged from 1.5 to 5.0 with higher values indicating higher levels of purpose. On the Clinical Dementia Rating Scale, 940 persons (62.1%) had no cognitive impairment, 121 (8.0%) had MCI, and 453 (29.9%) had dementia. In logistic regression models adjusted for age at death, sex, education, and race, higher purpose was associated with lower likelihood of MCI (odds ratio = .58; 95% confidence interval [CI]: .43, .79) and dementia (odds ratio = .49, 95% CI: .41, .59). Results were comparable after adjusting for depression (identified in 161 [10.6%]). Neither race nor education modified the association of purpose with cognitive diagnoses. CONCLUSIONS: Higher purpose in life is associated with lower likelihood of MCI and dementia in older black and white Brazilians.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Disfunção Cognitiva Tipo de estudo: Diagnostic_studies / Prognostic_studies / Qualitative_research Limite: Aged / Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: J Int Neuropsychol Soc Assunto da revista: NEUROLOGIA / PSICOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Disfunção Cognitiva Tipo de estudo: Diagnostic_studies / Prognostic_studies / Qualitative_research Limite: Aged / Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: J Int Neuropsychol Soc Assunto da revista: NEUROLOGIA / PSICOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido