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Potentially inappropriate prescribing to older adults in ambulatory care: prevalence and associated patient conditions.
Mino-León, Dolores; Sánchez-García, Sergio; Giraldo-Rodríguez, Liliana; Reyes-Morales, Hortensia.
Afiliação
  • Mino-León D; Clinical Epidemiology Research Unit, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
  • Sánchez-García S; Epidemiology and Health Services Research Unit, Aging Area, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
  • Giraldo-Rodríguez L; Research Division, Demographic Epidemiology and Social Determinants Department, Instituto Nacional de Geriatría, Secretaría de Salud, Mexico City, Mexico.
  • Reyes-Morales H; Center for Health Systems Research, Instituto Nacional de Salud Pública, Avenida Universidad #655, Santa María Ahuacatitlán, 62100, Cuernavaca, Morelos, Mexico. hortensia.reyes@insp.mx.
Eur Geriatr Med ; 10(4): 639-647, 2019 Aug.
Article em En | MEDLINE | ID: mdl-34652727
PURPOSE: To analyze potentially inappropriate prescribing (PIP), its prevalence and patient conditions associated with this phenomenon, in a cohort of older adults receiving outpatient care in Mexico. METHODS: Data from 1252 adults ≥ 60 years of age, from primary care centers were analyzed. Information included sociodemographic data, medications, chronic diseases, polypharmacy (≥ 5 medications), functional dependence, cognitive impairment and frailty. Three logistic regression models were employed to identify associations between PIP (according to the Beers criteria) and different variable combinations. RESULTS: A total of 41.8% of participants had at least one PIP. The most frequently identified PIPs involved nonsteroidal anti-inflammatory drugs (NSAIDs) and glibenclamide; clonazepam in patients with cognitive impairment; and interactions of warfarin with NSAIDs. In the multivariate analyses, Model 1 showed that frailty and polypharmacy were associated with PIP. In Model 2, only polypharmacy was associated with PIP. For Model 3, lower educational levels, taking hypoglycemics, nervous system disease drugs, antiasthmatics, gastrointestinal disease drugs and anti-inflammatories-antirheumatics and analgesics, were associated with PIP. CONCLUSION: PIP is common in outpatient treatment of health care services in Mexico. Its association with medical and nonmedical factors highlights the need to improve drug treatment quality focused on implementation of effective strategies, such as educative interventions, electronic medication safety alerts, and inclusion of pharmacists in the health team.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prevalence_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Eur Geriatr Med Ano de publicação: 2019 Tipo de documento: Article País de afiliação: México País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prevalence_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Eur Geriatr Med Ano de publicação: 2019 Tipo de documento: Article País de afiliação: México País de publicação: Suíça