Acute and Chronic Effects of Interval Training on the Immune System: A Systematic Review with Meta-Analysis.

Souza, Daniel; Vale, Arthur F; Silva, Anderson; Araújo, Murilo A S; de Paula Júnior, Célio A; de Lira, Claudio A B; Ramirez-Campillo, Rodrigo; Martins, Wagner; Gentil, Paulo

Souza, Daniel; Vale, Arthur F; Silva, Anderson; Araújo, Murilo A S; de Paula Júnior, Célio A; de Lira, Claudio A B; Ramirez-Campillo, Rodrigo; Martins, Wagner; Gentil, Paulo.

Afiliação

Souza D; Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia 74690-900, Brazil.
Vale AF; Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia 74690-900, Brazil.
Silva A; Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia 74690-900, Brazil.
Araújo MAS; Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia 74690-900, Brazil.
de Paula Júnior CA; Centro Universitário Araguaia, Goiânia 74223-060, Brazil.
de Lira CAB; Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia 74690-900, Brazil.
Ramirez-Campillo R; Department of Physical Activity Sciences, Universidad de Los Lagos, Santiago 8320000, Chile.
Martins W; Faculdade de Fisioterapia, Universidade de Brasília, Distrito Federal, Brasilia 70910-900, Brazil.
Gentil P; Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia 74690-900, Brazil.

Biology (Basel) ; 10(9)2021 Sep 03.

Article em En | MEDLINE | ID: mdl-34571745

RESUMO

PURPOSE: To summarize the evidence regarding the acute and chronic effects of interval training (IT) in the immune system through a systematic review with meta-analysis. DESIGN: Systematic review with meta-analysis. DATA SOURCE: English, Portuguese and Spanish languages search of the electronic databases Pubmed/Medline, Scopus, and SciELO. Eligibility criteria: Studies such as clinical trials, randomized cross-over trials and randomized clinical trials, investigating the acute and chronic effects of IT on the immune outcomes in humans. RESULTS: Of the 175 studies retrieved, 35 were included in the qualitative analysis and 18 in a meta-analysis. Within-group analysis detected significant acute decrease after IT on immunoglobulin A (IgA) secretory rate (n = 115; MD = -15.46 µg·min-1; 95%CI, -28.3 to 2.66; p = 0.02), total leucocyte count increase (n = 137; MD = 2.58 × 103 µL-1; 95%CI, 1.79 to 3.38; p < 0.001), increase in lymphocyte count immediately after exercise (n = 125; MD = 1.3 × 103 µL-1; 95%CI, 0.86 to 1.75; p < 0.001), and decrease during recovery (30 to 180 min post-exercise) (n = 125; MD = -0.36 × 103 µL-1;-0.57 to -0.15; p < 0.001). No effect was detected on absolute IgA (n = 127; MD = 47.5 µg·mL-1; 95%CI, -10.6 to 105.6; p = 0.11). Overall, IT might acutely reduce leucocyte function. Regarding chronic effects IT improved immune function without change leucocyte count. CONCLUSION: IT might provide a transient disturbance on the immune system, followed by reduced immune function. However, regular IT performance induces favorable adaptations on immune function.

Palavras-chave

aerobic capacity; high-intensity interval exercise; immunity; immunoglobulin A; immunologic monitoring; infectious disease; leukocytes; physical activity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Qualitative_research / Systematic_reviews Idioma: En Revista: Biology (Basel) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

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