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Reverse Myocardial Remodeling in Hypertrophic Cardiomyopathy: Little Explored Benefit of Exercise.
Petto, Jefferson; DE Oliveira, Edna C; DE Almeida, Raissa V A; DE Oliveira, Alice M; DO Amaral, Danielly S N; DE Pinna Júnior, Bráulio J B.
Afiliação
  • Petto J; Bahia Social University Center, Salvador, BA, BRAZIL.
  • DE Oliveira EC; Bahiana School of Medicine and Public Health, Salvador, BA, BRAZIL.
  • DE Almeida RVA; Actus-Cordios, Cardiovascular and Metabolic Rehabilitation, Salvador, BA, BRAZIL.
  • DE Oliveira AM; Bahia Adventist College, Cachoeira, BA, BRAZIL.
  • DO Amaral DSN; Bahia Adventist College, Cachoeira, BA, BRAZIL.
  • DE Pinna Júnior BJB; Bahia Social University Center, Salvador, BA, BRAZIL.
Int J Exerc Sci ; 14(2): 1018-1026, 2021.
Article em En | MEDLINE | ID: mdl-34567356
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease that causes myocardial remodeling. Physical exercise (PE) is a therapeutic resource used in Supervised Cardiac Rehabilitation (SCR) to improve Quality of Life (QL), reducing cardiovascular morbidity and mortality. Therefore, the aim of this study is to report how SCR using a personalized exercise prescription, promoted Reverse Myocardial Remodeling (RMR), improved functionality and QL of a patient with HCM. This is a case report of a 43-year-old sedentary female patient with a Body Mass Index (BMI) of 24.7 kg/m2. The patient was diagnosed with Septal Type Asymmetric HCM. Heart Failure (HF) grade III / IV, according to the New York Heart Association (NYHA), was initially treated with 40mg of Propranolol Hydrochloride twice a day, and presented with excessive fatigue, and angina. The echocardiogram showed a final diastolic volume (FDV) of 130 ml, a final systolic volume (FSV) of 44 ml, a left ventricular mass (LVM) of 236 g, interventricular septum thickness of 14 mm, left ventricular posterior wall (LVPW) thickness of 9 mm, left atrium diameter 46 mm, left ventricular end diastolic diameter of 52mm, septum/left ventricular wall ratio of 1.55 mm, and ejection fraction (EF) of 66% (Teicholz). It was obtained as a result of decreased FDV 130 vs. 102ml, decreased FSV 44 vs. 32 ml, decreased LVM 236 vs. 201 g, increased EF 66 vs. 69%, 26% improvement in QL, and 50% reduction in the dosage of Propranolol Hydrochloride. These results suggest that a personalized SCR program is an adjuvant treatment capable of promoting RMR and improving QL and functionality in a patient with HCM.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Aspecto: Patient_preference Idioma: En Revista: Int J Exerc Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Aspecto: Patient_preference Idioma: En Revista: Int J Exerc Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos