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Chenopodin as an anti-inflammatory compound.
Pompeu, Dávia Guimarães; Cordeiro, Helon Guimarães; Tonelli, Flávia Cristina Policarpo; Godin, Adriana Martins; Melo, Ivo Souza Ferraz de; Matsui, Tamires Cardoso; Rodrigues, Felipe Fernandes; Silva, Jose Antonio da; Coelho, Márcio de Matos; Machado, Renes Resende; Granjeiro, Paulo Afonso.
Afiliação
  • Pompeu DG; Campus Centro-Oeste Dona Lindu, Federal University of São João Del Rei (UFSJ), Divinopolis, Minas Gerais, Brazil.
  • Cordeiro HG; Department of Biochemistry and Tissue Biology Department, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
  • Tonelli FCP; Campus Centro-Oeste Dona Lindu, Federal University of São João Del Rei (UFSJ), Divinopolis, Minas Gerais, Brazil.
  • Godin AM; Department of Pharmaceutical Products School of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Melo ISF; Department of Pharmaceutical Products School of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Matsui TC; Department of Pharmaceutical Products School of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Rodrigues FF; Department of Pharmaceutical Products School of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Silva JAD; Campus Centro-Oeste Dona Lindu, Federal University of São João Del Rei (UFSJ), Divinopolis, Minas Gerais, Brazil.
  • Coelho MM; Department of Pharmaceutical Products School of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Machado RR; Department of Pharmaceutical Products School of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Granjeiro PA; Campus Centro-Oeste Dona Lindu, Federal University of São João Del Rei (UFSJ), Divinopolis, Minas Gerais, Brazil.
Nat Prod Res ; 36(17): 4435-4438, 2022 Sep.
Article em En | MEDLINE | ID: mdl-34544288
Chenopodin is an 11S-type globulin purified from Chenopodium quinoa seeds, which can bind carbohydrates and hemagglutinating human erythrocytes. The present study aimed to evaluate the N-terminal structure of the heterodimeric Chenopodin and its effects in models of inflammation. Chenopodin presented two subunits on its structure and has N-terminal homology with other Chenopodin in 92%. Chenopodin decreased paw edema and neutrophil recruitment induced by carrageenan in mice. Concluding, we demonstrated that Chenopodin exhibits in vivo anti-inflammatory activity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Edema / Anti-Inflamatórios Limite: Animals / Humans Idioma: En Revista: Nat Prod Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Edema / Anti-Inflamatórios Limite: Animals / Humans Idioma: En Revista: Nat Prod Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido