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Case Report: SARS-CoV-2 Mother-to-Child Transmission and Fetal Death Associated With Severe Placental Thromboembolism.
Marinho, Penélope Saldanha; da Cunha, Antonio José Ledo Alves; Chimelli, Leila; Avvad-Portari, Elyzabeth; Andreiuolo, Felipe da Matta; de Oliveira-Szejnfeld, Patrícia Soares; Mendes, Mayara Abud; Gomes, Ismael Carlos; Souza, Letícia Rocha Q; Guimarães, Marilia Zaluar; Goldman, Suzan Menasce; de Oliveira, Mariana Barros Genuíno; Rehen, Stevens; Amim, Joffre; Tovar-Moll, Fernanda; Prata-Barbosa, Arnaldo.
Afiliação
  • Marinho PS; Maternity School, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • da Cunha AJLA; Maternity School, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Chimelli L; Department of Pediatrics, D'Or Institute for Research and Education, Rio de Janeiro, Brazil.
  • Avvad-Portari E; Laboratory of Neuropathology, Rio de Janeiro State Brain Institute, Rio de Janeiro, Brazil.
  • Andreiuolo FDM; Department of Pathological Anatomy, Fernandes Figueira Institute, Fiocruz, Rio de Janeiro, Brazil.
  • de Oliveira-Szejnfeld PS; School of Medicine, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Mendes MA; Laboratory of Neuropathology, Rio de Janeiro State Brain Institute, Rio de Janeiro, Brazil.
  • Gomes IC; Diagnostic Imaging Department, Escola Paulista de Medicina, School of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
  • Souza LRQ; Diagnostic Imaging Department, D'Or Institute for Research and Education, Rio de Janeiro, Brazil.
  • Guimarães MZ; Stem Cell Laboratory, D'Or Institute for Research and Education, Rio de Janeiro, Brazil.
  • Goldman SM; Genetics Department, Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • de Oliveira MBG; Anatomic Pathology Service, Jesus Municipal Hospital, Rio de Janeiro, Brazil.
  • Rehen S; Stem Cell Laboratory, D'Or Institute for Research and Education, Rio de Janeiro, Brazil.
  • Amim J; Stem Cell Laboratory, D'Or Institute for Research and Education, Rio de Janeiro, Brazil.
  • Tovar-Moll F; Department of Phamacology, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Prata-Barbosa A; Diagnostic Imaging Department, Escola Paulista de Medicina, School of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
Front Med (Lausanne) ; 8: 677001, 2021.
Article em En | MEDLINE | ID: mdl-34485327
SARS-CoV-2 infection during pregnancy is not usually associated with significant adverse effects. However, in this study, we report a fetal death associated with mild COVID-19 in a 34-week-pregnant woman. The virus was detected in the placenta and in an unprecedented way in several fetal tissues. Placental abnormalities (MRI and anatomopathological study) were consistent with intense vascular malperfusion, probably the cause of fetal death. Lung histopathology also showed signs of inflammation, which could have been a contributory factor. Monitoring inflammatory response and coagulation in high-risk pregnant women with COVID-19 may prevent unfavorable outcomes, as shown in this case.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Front Med (Lausanne) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Front Med (Lausanne) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça