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CARD14-associated papulosquamous eruption (CAPE) in pediatric patients: Three additional cases and review of the literature.
Frare, Cindy P; Blumstein, Alli J; Paller, Amy S; Pieretti, Lia; Choate, Keith A; Bowcock, Anne M; Larralde, Margarita.
Afiliação
  • Frare CP; Department of Dermatology, Hospital Alemán, Buenos Aires, Argentina.
  • Blumstein AJ; Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Paller AS; Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Pieretti L; Dr Úraga Private Center for Skin Diseases, Guayaquil, Ecuador.
  • Choate KA; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Bowcock AM; Dermatology, Oncological Sciences and Genetics & Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Larralde M; Department of Dermatology, Hospital Alemán, Buenos Aires, Argentina.
Pediatr Dermatol ; 38(5): 1237-1242, 2021 Sep.
Article em En | MEDLINE | ID: mdl-34448248
CARD14-associated papulosquamous eruption (CAPE) is a proposed term that encompasses features ranging from psoriasis to pityriasis rubra pilaris (PRP) in association with CARD14 mutations. The early onset of the disease, prominent facial involvement, family history of an autosomal dominant trait, and poor response to conventional treatment are characteristics of CAPE that distinguish it from classical psoriasis and PRP. We describe the clinical features, family history, and response to therapy in three unrelated children with CAPE and compare these characteristics with those of previously described pediatric patients. Testing for CARD14 mutations in children with early onset of features of psoriasis or pityriasis rubra pilaris and resistance to conventional therapy should be considered.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pitiríase Rubra Pilar / Exantema Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Child / Humans Idioma: En Revista: Pediatr Dermatol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Argentina País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pitiríase Rubra Pilar / Exantema Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Child / Humans Idioma: En Revista: Pediatr Dermatol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Argentina País de publicação: Estados Unidos