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Palliative sedation in patients with advanced cancer in a specialized unit in a middle-income country: A retrospective cohort study.
de Araujo, Carolina Záu Serpa; de Araújo, Laís Záu Serpa; Nassar Junior, Antonio Paulo.
Afiliação
  • de Araujo CZS; Palliative Care Unit, Santa Casa de Misericordia, Maceió, Brazil.
  • de Araújo LZS; Discipline of Bioethics, Universidade Estadual de Ciências da Saúde de Alagoas, Maceió, Brazil.
  • Nassar Junior AP; A.C. Camargo Cancer Center, São Paulo, Brazil.
Palliat Support Care ; 20(4): 491-495, 2022 08.
Article em En | MEDLINE | ID: mdl-34425935
OBJECTIVE: To describe the 5-year practice on palliative sedation in a specialized palliative care unit in a deprived region in Brazil, and to compare survival of patients with advanced cancer who were and were not sedated during their end-of-life care. METHOD: Retrospective cohort study in a tertiary teaching hospital. We described the practice of palliative sedation and compared the survival time between patients who were and were not sedated in their last days of life. RESULTS: We included 906 patients who were admitted to the palliative care unit during the study period, of whom, 92 (10.2%) received palliative sedation. Patients who were sedated were younger, presented with higher rates of delirium, and reported more pain, suffering, and dyspnea than those who were not sedated. Median hospital survival of patients who received palliative sedation was 9.30 (CI 95%, 7.51-11.81) days and of patients who were not sedated was 8.2 (CI 95%, 7.3-9.0) days (P = 0.31). Adjusted for age and sex, palliative sedation was not significantly associated with hospital survival (hazard ratio = 0.93; CI 95%, 0.74-1.15). SIGNIFICANCE OF RESULTS: Palliative sedation can be accomplished even in a deprived area. Delirium, dyspnea, and pain were more common in patients who were sedated. Median survival was not reduced in patients who were sedated.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Assistência Terminal / Delírio / Neoplasias Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Palliat Support Care Assunto da revista: TERAPEUTICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Assistência Terminal / Delírio / Neoplasias Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Palliat Support Care Assunto da revista: TERAPEUTICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido