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Clinical outcomes of cystic fibrosis patients with hemoptysis treated with bronchial artery embolization.
Silveira, Marília Amaral Peixoto da; Silveira, Patrícia Amaral Peixoto da; Beltrami, Flávia Gabe; Scaffaro, Leandro Armani; Dalcin, Paulo de Tarso Roth.
Afiliação
  • Silveira MAPD; . Programa de Pós-Graduação em Ciências Pneumológicas, Universidade Federal do Rio Grande do Sul - UFRGS - Porto Alegre (RS) Brasil.
  • Silveira PAPD; . Serviço de Pneumologia, Hospital de Clínicas de Porto Alegre - HCPA - Porto Alegre (RS) Brasil.
  • Beltrami FG; . Faculdade de Medicina, Universidade Federal de Pelotas, Pelotas (RS) Brasil.
  • Scaffaro LA; . Programa de Pós-Graduação em Ciências Pneumológicas, Universidade Federal do Rio Grande do Sul - UFRGS - Porto Alegre (RS) Brasil.
  • Dalcin PTR; . Serviço de Pneumologia, Hospital de Clínicas de Porto Alegre - HCPA - Porto Alegre (RS) Brasil.
J Bras Pneumol ; 47(4): e20200557, 2021.
Article em En, Pt | MEDLINE | ID: mdl-34406223
OBJECTIVE: Massive hemoptysis is one of the most serious complications in patients with cystic fibrosis (CF). This study aimed to evaluate the hemoptysis-free period following bronchial and non-bronchial artery embolization (BAE/non-BAE) in CF patients and to investigate predictors of recurrent bleeding and mortality by any cause. METHODS: This was a retrospective cohort study of CF patients ≥ 16 years of age undergoing BAE/non-BAE for hemoptysis between 2000 and 2017. RESULTS: We analyzed 39 hemoptysis episodes treated with BAE/non-BAE in 17 CF patients. Hemoptysis recurrence rate was 56.4%. Of the sample as a whole, 3 (17.6%) were hemoptysis-free during the study period, 2 (11.8%) underwent lung transplantation, and 3 (17.6%) died. The median hemoptysis-free period was 17 months. The median hemoptysis-free period was longer in patients with chronic infection with Pseudomonas aeruginosa (31 months; 95% CI: 0.00-68.5) than in those without that type of infection (4 months; 95% CI: 1.8-6.2; p = 0.017). However, this association was considered weak, and its clinical significance was uncertain due to the small number of patients without that infection. CONCLUSIONS: BAE appears to be effective in the treatment of hemoptysis in patients with CF.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Cística / Embolização Terapêutica Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies Limite: Humans Idioma: En / Pt Revista: J Bras Pneumol Ano de publicação: 2021 Tipo de documento: Article País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Cística / Embolização Terapêutica Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies Limite: Humans Idioma: En / Pt Revista: J Bras Pneumol Ano de publicação: 2021 Tipo de documento: Article País de publicação: Brasil