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Air Pollution: A Neglected Risk Factor for Dementia in Latin America and the Caribbean.
Dos Santos, Nathália Villa; Yariwake, Victor Yuji; Marques, Karina do Valle; Veras, Mariana Matera; Fajersztajn, Laís.
Afiliação
  • Dos Santos NV; Laboratório de Poluição Ambiental, Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
  • Yariwake VY; Departamento de Saude Ambiental, Faculdade de Saude Publica, Universidade de São Paulo, São Paulo, Brazil.
  • Marques KDV; Laboratório de Poluição Ambiental, Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
  • Veras MM; Departamento de Cirurgia, Universidade Federal de Uberlandia, Uberlândia, Brazil.
  • Fajersztajn L; Laboratório de Poluição Ambiental, Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Front Neurol ; 12: 684524, 2021.
Article em En | MEDLINE | ID: mdl-34367051
The risk of dementia and Alzheimer's disease in Latin America and the Caribbean (LAC) rises with increasing age and polluted air. Currently, at least 172 million people breathe unhealthy levels of air pollution in LAC countries. Several cohort studies have indicated that air pollution increases the risk of developing dementia and neurodegenerative diseases, but the mechanisms underlying the association are still not clear. Air pollution causes and aggravates five established risk factors for dementia (obesity, hypertension, stroke, diabetes mellitus, and heart diseases) and is linked to three other risk factors (physical inactivity, cognitive inactivity, and depression). Some of these risk factors could be mediating the association between air pollution and dementia. Reducing the risks for dementia is crucial and urgently needed in LAC countries. There is room for improving air quality in many urban areas in the LAC region and other low- and middle-income countries (LMICs), a routealready explored by many urban areas in developing regions. Moreover, reducing air pollution has proved to improve health outcomes before. In this article, we propose that despite the ongoing and valid scientific discussion, if air pollution can or cannot directly affect the brain and cause or aggravate dementia, we are ready to consider air pollution as a potentially modifiable risk factor for dementia in LAC and possibly in other LMICs. We suggest that controlling and reducing current air pollution levels in LAC and other LMIC regions now could strongly contribute.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Front Neurol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Front Neurol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça