Multiple sclerosis in Peru: National prevalence study using capture-recapture analysis.
Mult Scler Relat Disord
; 55: 103147, 2021 Oct.
Article
em En
| MEDLINE
| ID: mdl-34332455
BACKGROUND: There is scarce epidemiological data on Multiple Sclerosis (MS) in Latin America. National epidemiological studies are needed to guide the health policy related to MS. OBJECTIVE: To determine MS national prevalence in Peru and describe clinical and epidemiological characteristics of the disease. METHODS: We conducted a cross-sectional prevalence study in Peru's four largest regions using two sources. We included adult patients diagnosed with MS by a neurologist using the McDonald criteria. We performed a capture-recapture analysis using the nearly unbiased estimator model, and calculated prevalence as the proportion of the adult Peruvian population in 2016. Additionally, we summarized patients epidemiological and clinical characteristics. RESULTS: We identified 417 cases: 135 from the first source and 282 from the one. We found a point prevalence of 9.12 cases per 100 000 inhabitants (95% CI: 5.6 - 12.6). The age range was 35 to 45 years-old, and 51.9% were female. The most common type of MS was relapsing-remitting (79.3%) and the most frequent treatment was subcutaneous IFN-1b (40.7%). CONCLUSION: Peru has a medium MS prevalence compared to other Latin American countries. Lima is the region with the highest number of cases, with similar clinical characteristics to other countries in the region.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esclerose Múltipla
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
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Female
/
Humans
/
Middle aged
País/Região como assunto:
America do sul
/
Peru
Idioma:
En
Revista:
Mult Scler Relat Disord
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Peru
País de publicação:
Holanda