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Multiple sclerosis in Peru: National prevalence study using capture-recapture analysis.
O, Gonzales-Gamarra; C, Alva-Diaz; K, Pacheco-Barrios; W, Aguirre-Quispe; M, Malaga; J, Inca; E, Rojas; C, Caparó-Zamalloa; M, Montalvan; E, Salcedo; Am, Solis-Quispe; J, Barreto; M, Rojas-Benites; A, Chereque; Ml, Rodríguez.
Afiliação
  • O GG; Peruvian Committee for Treatment and Research in Multiple Sclerosis (PECTRIMS), Lima, Peru.
  • C AD; Grupo de Investigación Neurociencia, Efectividad Clínica y Salud Pública, Universidad Científica del Sur, Lima, Perú.
  • K PB; SYNAPSIS Mental Health and Neurology Non-Profit organization, Lima, Peru; Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud. Universidad San Ignacio de Loyola, Lima, Peru.
  • W AQ; Instituto Nacional de Ciencias Neurológicas, Lima, Perú.
  • M M; Facultad de Medicina Humana, Universidad de San Martín de Porres, Lima, Perú.
  • J I; Servicio de Neurología, Hospital Nacional "Guillermo Almenara Irigoyen" - EsSalud, Lima, Peru.
  • E R; Servicio de Neurología, Hospital Nacional "Guillermo Almenara Irigoyen" - EsSalud, Lima, Peru; Asociación de pacientes con Esclerosis Múltiple en el Perú, Lima, Peru.
  • C CZ; Basic Research Center in Dementias and Central Nervous System Demyelinating Diseases, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
  • M M; Hospital Victor Lazarte Echegaray - EsSalud, Trujillo, Perú.
  • E S; Servicio de Neurología, Hospital EsSalud Arequipa, Arequipa, Peru.
  • Am SQ; Servicio de Neurología, Hospital Nacional Arzobispo Loayza, Lima, Peru.
  • J B; Servicio de Neurología, Hospital Nacional Arzobispo Loayza, Lima, Peru.
  • M RB; Servicio de Neurología. Hospital Regional Docente de Trujillo-MINSA.
  • A C; Asociación de pacientes con Esclerosis Múltiple en el Perú, Lima, Peru.
  • Ml R; Asociación de pacientes con Esclerosis Múltiple en el Perú, Lima, Peru.
Mult Scler Relat Disord ; 55: 103147, 2021 Oct.
Article em En | MEDLINE | ID: mdl-34332455
BACKGROUND: There is scarce epidemiological data on Multiple Sclerosis (MS) in Latin America. National epidemiological studies are needed to guide the health policy related to MS. OBJECTIVE: To determine MS national prevalence in Peru and describe clinical and epidemiological characteristics of the disease. METHODS: We conducted a cross-sectional prevalence study in Peru's four largest regions using two sources. We included adult patients diagnosed with MS by a neurologist using the McDonald criteria. We performed a capture-recapture analysis using the nearly unbiased estimator model, and calculated prevalence as the proportion of the adult Peruvian population in 2016. Additionally, we summarized patients epidemiological and clinical characteristics. RESULTS: We identified 417 cases: 135 from the first source and 282 from the one. We found a point prevalence of 9.12 cases per 100 000 inhabitants (95% CI: 5.6 - 12.6). The age range was 35 to 45 years-old, and 51.9% were female. The most common type of MS was relapsing-remitting (79.3%) and the most frequent treatment was subcutaneous IFN-1b (40.7%). CONCLUSION: Peru has a medium MS prevalence compared to other Latin American countries. Lima is the region with the highest number of cases, with similar clinical characteristics to other countries in the region.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Múltipla Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Middle aged País/Região como assunto: America do sul / Peru Idioma: En Revista: Mult Scler Relat Disord Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Peru País de publicação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Múltipla Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Middle aged País/Região como assunto: America do sul / Peru Idioma: En Revista: Mult Scler Relat Disord Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Peru País de publicação: Holanda