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Neurobiological approaches of high-fat diet intake in early development and their impact on mood disorders in adulthood: A systematic review.
Ortiz-Valladares, Minerva; Pedraza-Medina, Ricardo; Pinto-González, María Fernanda; Muñiz, Jorge Guzmán; Gonzalez-Perez, Oscar; Moy-López, Norma Angélica.
Afiliação
  • Ortiz-Valladares M; Medical Science Postgraduate Program, School of Medicine, University of Colima, Colima, Mexico.
  • Pedraza-Medina R; Medical Science Postgraduate Program, School of Medicine, University of Colima, Colima, Mexico.
  • Pinto-González MF; Medical Science Postgraduate Program, School of Medicine, University of Colima, Colima, Mexico.
  • Muñiz JG; Laboratory of Neuroscience, School of Psychology, University of Colima, Colima, Mexico.
  • Gonzalez-Perez O; Laboratory of Neuroscience, School of Psychology, University of Colima, Colima, Mexico.
  • Moy-López NA; Laboratory of Neuroscience, School of Psychology, University of Colima, Colima, Mexico. Electronic address: moynor@ucol.mx.
Neurosci Biobehav Rev ; 129: 218-230, 2021 10.
Article em En | MEDLINE | ID: mdl-34324919
The early stage of development is a vulnerable period for progeny neurodevelopment, altering cytogenetic and correct cerebral functionality. The exposure High-Fat Diet (HFD) is a factor that impacts the future mental health of individuals. This review analyzes possible mechanisms involved in the development of mood disorders in adulthood because of maternal HFD intake during gestation and lactation, considering previously reported findings in the last five years, both in humans and animal models. Maternal HFD could induce alterations in mood regulation, reported as increased stress response, anxiety-like behavior, and depressive-like behavior. These changes were mostly related to HPA axis dysregulations and neuroinflammatory responses. In conclusion, there could be a relationship between HFD consumption during the early stages of life and the development of psychopathologies during adulthood. These findings provide guidelines for the understanding of possible mechanisms involved in mood disorders, however, there is still a need for more human clinical studies that provide evidence to improve the understanding of maternal nutrition and future mental health outcomes in the offspring.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Dieta Hiperlipídica Tipo de estudo: Etiology_studies / Guideline / Prognostic_studies / Systematic_reviews Limite: Adult / Animals / Female / Humans / Pregnancy Idioma: En Revista: Neurosci Biobehav Rev Ano de publicação: 2021 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Dieta Hiperlipídica Tipo de estudo: Etiology_studies / Guideline / Prognostic_studies / Systematic_reviews Limite: Adult / Animals / Female / Humans / Pregnancy Idioma: En Revista: Neurosci Biobehav Rev Ano de publicação: 2021 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos