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Gastric Mixed Neuroendocrine Non-Neuroendocrine Neoplasms: A Western Center Case Series.
Ramos, Marcus Fernando Kodama Pertille; Pereira, Marina Alessandra; Arabi, Arthur Youssif Mota; Mazepa, Melissa Mello; Dias, Andre Roncon; Ribeiro, Ulysses; Zilberstein, Bruno; Nahas, Sergio Carlos.
Afiliação
  • Ramos MFKP; Faculdade de Medicina, Instituto do Cancer, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, Sao Paulo 01246-000, Brazil.
  • Pereira MA; Faculdade de Medicina, Instituto do Cancer, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, Sao Paulo 01246-000, Brazil.
  • Arabi AYM; Faculdade de Medicina, Instituto do Cancer, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, Sao Paulo 01246-000, Brazil.
  • Mazepa MM; Faculdade de Medicina, Instituto do Cancer, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, Sao Paulo 01246-000, Brazil.
  • Dias AR; Faculdade de Medicina, Instituto do Cancer, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, Sao Paulo 01246-000, Brazil.
  • Ribeiro U; Faculdade de Medicina, Instituto do Cancer, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, Sao Paulo 01246-000, Brazil.
  • Zilberstein B; Faculdade de Medicina, Instituto do Cancer, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, Sao Paulo 01246-000, Brazil.
  • Nahas SC; Faculdade de Medicina, Instituto do Cancer, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, Sao Paulo 01246-000, Brazil.
Med Sci (Basel) ; 9(3)2021 06 25.
Article em En | MEDLINE | ID: mdl-34201925
BACKGROUND: Mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) represent a rare tumor composed of adenocarcinoma and neuroendocrine carcinoma components. This study reports a case series of gastric MiNEN and discusses issues related to its diagnosis, management, and outcomes. METHODS: We retrospectively analyzed data from patients with gastric MiNEN who underwent surgical resection at our service from 2009 to 2020. Patients with gastric adenocarcinoma served as a comparison group. Clinical, pathologic, and surgical characteristics were compared. RESULTS: During the selected period, 5 gastric MiNEN patients and 597 patients with gastric adenocarcinoma were included. Among the clinical variables, age, sex, BMI, and laboratory exams were similar between the two groups. Only ASA classification was different (p = 0.015). Pathological variables such as tumor size, lymphovascular invasion, number of retrieved lymph nodes, and pTNM staging were also similar between both groups. Lastly, early surgical outcomes and long-term survival did not differ between gastric MiNEN and adenocarcinoma patients. CONCLUSION: A MiNEN is a rare tumor that represents less than 1% of GC patients undergoing curative treatment, and demonstrated clinicopathological characteristics and outcomes similar to gastric adenocarcinoma.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Neuroendócrino / Neoplasias Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Humans Idioma: En Revista: Med Sci (Basel) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Neuroendócrino / Neoplasias Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Humans Idioma: En Revista: Med Sci (Basel) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça