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Pulmonary function evaluation after hospital discharge of patients with severe COVID-19.
Polese, Jessica; Sant'Ana, Larissa; Moulaz, Isac Ribeiro; Lara, Izabella Cardoso; Bernardi, Julia Muniz; Lima, Marina Deorce de; Turini, Elaína Aparecida Silva; Silveira, Gabriel Carnieli; Duarte, Silvana; Mill, José Geraldo.
Afiliação
  • Polese J; Departamento de Pneumologia, Universidade Federal do Espirito Santo, Vitoria, ES, BR.
  • Sant'Ana L; Universidade Federal do Espirito Santo, Vitoria, ES, BR.
  • Moulaz IR; Universidade Federal do Espirito Santo, Vitoria, ES, BR.
  • Lara IC; Universidade Federal do Espirito Santo, Vitoria, ES, BR.
  • Bernardi JM; Universidade Federal do Espirito Santo, Vitoria, ES, BR.
  • Lima MD; Universidade Federal do Espirito Santo, Vitoria, ES, BR.
  • Turini EAS; Universidade Federal do Espirito Santo, Vitoria, ES, BR.
  • Silveira GC; Universidade Federal do Espirito Santo, Vitoria, ES, BR.
  • Duarte S; Departamento de Pneumologia, Universidade Federal do Espirito Santo, Vitoria, ES, BR.
  • Mill JG; Departamento de Ciencias Fisiologicas, Centro de Ciencias da Saude, Universidade Federal do Espirito Santo, Vitoria, ES, BR.
Clinics (Sao Paulo) ; 76: e2848, 2021.
Article em En | MEDLINE | ID: mdl-34190851
OBJECTIVES: Coronavirus disease 2019 (COVID-19) may be associated with prolonged symptoms and post-recovery health impairment. This study aimed to evaluate the persistence of symptoms, lung function, and pulmonary diffusion for carbon monoxide (DLCO) in patients between 15 and 30 days after hospital discharge after admission for severe COVID-19. METHODS: The evaluation consisted of 1) comparative analysis between the initial symptoms and symptoms still present at the post-discharge evaluation 2) analysis of the chest images obtained during hospitalization, and 3) conducting spirometry, plethysmography, and DLCO assessment. RESULTS: Forty-one patients who were hospitalized for 16±8 days with severe COVID-19 were included. Patients were predominantly men (73%) and had a mean age of 51±14 years. The most frequent comorbidities were arterial hypertension (51%) and diabetes mellitus (37%). Pulmonary evaluation was performed a mean of 36 days after the onset of symptoms, with the most frequent persistent symptoms being dyspnea (83%) and coughing (54%). Approximately 93% of patients still had at least one symptom, and 20% had more than five symptoms. Chest imaging revealed a typical pattern of COVID-19 on X-ray (93%) and computer tomography (95%). Lung function test results showed a restrictive pattern with a reduction in forced vital capacity (FVC) in 54% of individuals, with an average FVC of 78±14%. A reduction in DLCO was observed in 79% of patients. CONCLUSIONS: We observed a high prevalence of symptoms, in addition to a significant change in lung function and DLCO, in the post-discharge assessment of patients requiring hospitalization after admission for COVID-19.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alta do Paciente / COVID-19 Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Humans / Male / Middle aged Idioma: En Revista: Clinics (Sao Paulo) Assunto da revista: MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alta do Paciente / COVID-19 Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Humans / Male / Middle aged Idioma: En Revista: Clinics (Sao Paulo) Assunto da revista: MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos