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Long-Term Neurodevelopmental Outcomes after Moderate and Late Preterm Birth: A Systematic Review.
Fernández de Gamarra-Oca, Lexuri; Ojeda, Natalia; Gómez-Gastiasoro, Ainara; Peña, Javier; Ibarretxe-Bilbao, Naroa; García-Guerrero, M Acebo; Loureiro, Begoña; Zubiaurre-Elorza, Leire.
Afiliação
  • Fernández de Gamarra-Oca L; Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Bilbao, Bizkaia, Spain.
  • Ojeda N; Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Bilbao, Bizkaia, Spain. Electronic address: nojeda@deusto.es.
  • Gómez-Gastiasoro A; Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Bilbao, Bizkaia, Spain.
  • Peña J; Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Bilbao, Bizkaia, Spain.
  • Ibarretxe-Bilbao N; Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Bilbao, Bizkaia, Spain.
  • García-Guerrero MA; Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Bilbao, Bizkaia, Spain.
  • Loureiro B; Neonatal Unit, Cruces University Hospital, Biocruces Bizkaia Health Research Institute, Barakaldo, Bizkaia, Spain.
  • Zubiaurre-Elorza L; Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Bilbao, Bizkaia, Spain.
J Pediatr ; 237: 168-176.e11, 2021 Oct.
Article em En | MEDLINE | ID: mdl-34171360
OBJECTIVE: To systematically review and perform meta-analyses on the long-term neurodevelopmental outcomes of adults born moderate and late preterm (MLPT) in relation to cognitive functioning and psychiatric disorders. STUDY DESIGN: A search was conducted to identify any studies that involved prematurity in adulthood. From these studies, reports that included a group of MLPT adults and included description of cognitive and/or mental health domains (including specific long-term outcomes) were selected. RESULTS: In total, 155 publications were identified, but only 16 papers met the inclusion criteria. A small effect size (g = 0.38) was found in MLPT to demonstrate poorer intellectual performance compared with those born at term. Moreover, MLPT adults exhibited greater odds for any psychiatric (OR 1.14), substance use (OR 1.16), mood (OR 1.06), and psychotic disorders (OR 1.40). CONCLUSIONS: Despite inconsistency due to the methodologic differences between the selected studies, MLPT showed minor long-term effects into adulthood. However, more studies are needed, because prematurity seems to confer some vulnerability to biological and environmental factors that enhance susceptibility to adverse neurodevelopment outcomes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos do Neurodesenvolvimento Tipo de estudo: Diagnostic_studies / Prognostic_studies / Systematic_reviews Limite: Adult / Humans / Newborn Idioma: En Revista: J Pediatr Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Espanha País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos do Neurodesenvolvimento Tipo de estudo: Diagnostic_studies / Prognostic_studies / Systematic_reviews Limite: Adult / Humans / Newborn Idioma: En Revista: J Pediatr Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Espanha País de publicação: Estados Unidos