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Cross-sectional study on intestinal parasite infections in different ecological zones of the Department of La Paz, Bolivia.
Aruni Chura, Jorge; Macchioni, Fabio; Furzi, Federica; Balboa, Victor; Mercado, Érika; Gómez, José; Rojas Gonzales, Patricia; Poma, Veronica; Loup, Armando; Roselli, Mimmo; Halkier, Percy; Montresor, Antonio; Olliaro, Piero; Bartoloni, Alessandro; Spinicci, Michele; Gabrielli, Simona.
Afiliação
  • Aruni Chura J; Instituto Nacional de Laboratorios de Salud (INLASA) - Ministerio de Salud, La Paz, Plurinational State of Bolivia.
  • Macchioni F; Dipartimento di Scienze Veterinarie, Università di Pisa, Pisa, Italy.
  • Furzi F; Dipartimento di Sanità Pubblica e Malattie Infettive, Università di Roma Sapienza, Roma, Italy.
  • Balboa V; Instituto Nacional de Laboratorios de Salud (INLASA) - Ministerio de Salud, La Paz, Plurinational State of Bolivia.
  • Mercado É; Instituto Nacional de Laboratorios de Salud (INLASA) - Ministerio de Salud, La Paz, Plurinational State of Bolivia.
  • Gómez J; Instituto Nacional de Laboratorios de Salud (INLASA) - Ministerio de Salud, La Paz, Plurinational State of Bolivia.
  • Rojas Gonzales P; Caja Petrolera Hospital, Camiri, Plurinational State of Bolivia.
  • Poma V; Escuela de Salud del Chaco Tekove Katu, Gutierrez, Plurinational State of Bolivia.
  • Loup A; Ministerio de Salud, Programa Nacional de Zoonosis, La Paz, Plurinational State of Bolivia.
  • Roselli M; Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
  • Halkier P; Immunization, Pan-American Health Organization, La Paz, Plurinational State of Bolivia.
  • Montresor A; Department of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.
  • Olliaro P; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Bartoloni A; Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
  • Spinicci M; Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
  • Gabrielli S; Dipartimento di Sanità Pubblica e Malattie Infettive, Università di Roma Sapienza, Roma, Italy.
One Health ; 13: 100271, 2021 Dec.
Article em En | MEDLINE | ID: mdl-34159246
We performed a cross-sectional parasitological survey to assess the prevalence of protozoa and helminth infection among 275 school-age children (SAC) living in rural and peri-urban areas located in different ecological zones of the Department of La Paz, Bolivia. Public health activities for the control of STH, based on the biannual administration of mebendazole to preschool and school children are implemented at national level since 1986. We found an overall prevalence of 82.2% for intestinal parasites, including protozoa (80%) and helminths (23.3%). Blastocystis and Entamoeba coli were the most prevalent protozoa (found in 44% and 20.7% of the SAC enrolled); as for helminths, Ascaris lumbricoides and Hymenolepis nana were diagnosed in 14.5% and 3.3% of the children, respectively, followed by Trichuris trichiura 1.4%, Enterobius vermicularis 1.4%, Strongyloides stercoralis 0.7% and hookworms 0.7%. Molecular characterization of Blastocystis positive samples evidenced three different subtypes (ST1, ST2, ST3) highlighting the risk of transmission also from animal reservoir. We found a significant difference in the distribution of intestinal parasitic infection (IPIs) by ecological zone (44/74. 59% in Andean highlands, 94/170, 88% in tropical lowlands and 88/94, 94% in the Yungas, p < 0.001). Access to potable water (OR 0.1 95%CI 0.02-0.5, p = 0.004) and the habit of boiling drinking water (OR 0.3, 95% CI 0.2-0.7, p = 0.004) showed an independent association with a lower risk of all IPIs and STHs, respectively. The very low prevalence of STH infections of moderate heavy intensity demonstrate that periodical deworming has been successful in reducing the morbidity due to these parasites, however the high prevalence of protozoa demonstrate that sanitation is still problematic and there is a relevant contamination of the environment with human faeces. Significant efforts are still needed to reduce IPIs transmission and to improve health and sanitation in this area.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies País/Região como assunto: America do sul / Bolivia Idioma: En Revista: One Health Ano de publicação: 2021 Tipo de documento: Article País de publicação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies País/Região como assunto: America do sul / Bolivia Idioma: En Revista: One Health Ano de publicação: 2021 Tipo de documento: Article País de publicação: Holanda