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Quality of life in keratoconus: evaluation with Keratoconus Outcomes Research Questionnaire (KORQ).
Pinto, Roberto Damian Pacheco; Abe, Ricardo Yuji; Gomes, Flávia Cid; Barbisan, Paulo Rodolfo Tagliari; Martini, Alexandre Fattah; de Almeida Borges, Daniel; Fernandes, Arthur Gustavo; Arieta, Carlos Eduardo Leite; Alves, Monica.
Afiliação
  • Pinto RDP; Department of Ophthalmology and Otorhinolaryngology, University of Campinas, Campinas, São Paulo, Brazil. rpacheco42@gmail.com.
  • Abe RY; Department of Ophthalmology and Otorhinolaryngology, University of Campinas, Campinas, São Paulo, Brazil.
  • Gomes FC; Department of Ophthalmology and Otorhinolaryngology, University of Campinas, Campinas, São Paulo, Brazil.
  • Barbisan PRT; Department of Ophthalmology and Otorhinolaryngology, University of Campinas, Campinas, São Paulo, Brazil.
  • Martini AF; Department of Ophthalmology and Otorhinolaryngology, University of Campinas, Campinas, São Paulo, Brazil.
  • de Almeida Borges D; Department of Ophthalmology and Otorhinolaryngology, University of Campinas, Campinas, São Paulo, Brazil.
  • Fernandes AG; Departamento de Oftalmologia e Ciências Visuais, Escola Paulista de Medicina, Universidade Federal de São Paulo - UNIFESP, São Paulo, SP, Brazil.
  • Arieta CEL; Department of Ophthalmology and Otorhinolaryngology, University of Campinas, Campinas, São Paulo, Brazil.
  • Alves M; Department of Ophthalmology and Otorhinolaryngology, University of Campinas, Campinas, São Paulo, Brazil.
Sci Rep ; 11(1): 12970, 2021 06 21.
Article em En | MEDLINE | ID: mdl-34155238
To assess the quality of life of keratoconus patients using the Keratoconus Outcomes Research Questionnaire (KORQ), translated and validated in Portuguese language. The KORQ is the only validated keratoconus specific questionnaire and has a high rating for its psychometric properties. This cross-sectional study enrolled 100 keratoconus patients from a tertiary referral eye hospital between April 2018 and June 2019. Associations between age, sex, allergic conjunctivitis, keratoconus stage, best-corrected visual acuity (BCVA), maximum simulated keratometry (Kmax), steep keratometry (K2), pachymetry, treatments performed, hydrops, and KORQ scores were evaluated using univariate (Wilcoxon test and the Kruskal Wallis test) and multivariate linear regression with stepwise backward modeling. Lower KORQ scores are associated with better quality of life, whereas, higher scores are associated with greater impairment of functional activities and symptoms. Among the 100 patients, mild, moderate, and severe keratoconus were observed in 15%, 46% and 39% of participants, respectively. Univariate analysis showed lower function scores values, with male sex (p < 0.05) and both functional and symptom scores were significantly associated with BCVA < 0.3 (LogMAR) (p < 0.05). Multivariate analysis indicated significantly lower functional scores in individuals with BCVA < 0.3 (LogMAR) (p < 0.001) and those with a history of crosslinking treatment (p = 0.022), while symptom scores were only significantly associated with only BCVA < 0.3 (LogMAR) (p < 0.001). In patients with keratoconus, BCVA in the better eye and history of crosslinkig were factors associated with better quality of life scores using the KORQ.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Ceratocone Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Ceratocone Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido