Protein Predictive Modeling and Simulation of Mutations of Presenilin-1 Familial Alzheimer's Disease on the Orthosteric Site.

Soto-Ospina, Alejandro; Araque Marín, Pedronel; Bedoya, Gabriel; Sepulveda-Falla, Diego; Villegas Lanau, Andrés

Soto-Ospina, Alejandro; Araque Marín, Pedronel; Bedoya, Gabriel; Sepulveda-Falla, Diego; Villegas Lanau, Andrés.

Afiliação

Soto-Ospina A; Faculty of Medicine, Group Molecular Genetics, University of Antioquia, Medellín, Colombia.
Araque Marín P; Faculty of Medicine, Group Neuroscience of Antioquia, University of Antioquia, Medellín, Colombia.
Bedoya G; School of Life Sciences, Research and Innovation in Chemistry Formulations Group, EIA University, Envigado, Colombia.
Sepulveda-Falla D; Faculty of Medicine, Group Molecular Genetics, University of Antioquia, Medellín, Colombia.
Villegas Lanau A; Faculty of Medicine, Group Neuroscience of Antioquia, University of Antioquia, Medellín, Colombia.

Front Mol Biosci ; 8: 649990, 2021.

Article em En | MEDLINE | ID: mdl-34150846

Palavras-chave

familiar Alzheimer's disease mutations; modeling; presenilin-1; quantum mechanics/molecular mechanics; simulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Mol Biosci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Suíça

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